Search Results - imaging+agent

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Micro-Dose Calibrator for Pre-clinical Radiotracer Assays

Abstract: Molecular imaging is a disease-specific targeting modality that promises much more accurate diagnoses of serious diseases such as cancer and infections. Agents are being continually developed with a view to clinical translation, with several such therapies requiring measurement of very small doses. Currently, there is no way of accurately...

Published: 4/8/2024 | Inventor(s): Stephen Adler

Keywords(s): Adler, Dose Calibrator, imaging agent, Medical Radioisotope

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Immunology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Medical Devices

Zirconium-89 PET Imaging Agent for Cancer

Abstract: Researchers at the NCI Radiation Oncology Branch and NIH CIT Center for Molecular Modeling developed a tetrahydroxamate chelation technology that provides a more-stable Zr-89 complex as an immuno-PET cancer imaging agent. In either the linear or the macrocyclic form, the tetrahydroxamate complexes exhibit greater stability as chelating agents...

Published: 5/23/2024 | Inventor(s): Francois Guerard, Yong-Sok Lee, Martin Brechbiel

Keywords(s): imaging agent, PET, zirconium-89

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Research Materials

Enhanced Tissue Clearing Solution, Clearing-Enhanced 3D (Ce3D), Compatible with Advanced Fluorescence Microscopy Imaging

NIH immunologists have created a solution, Clearing-enhanced 3D (Ce3D), that can be used to make entire organs extremely transparent (top right panel). This allows the tissue to be imaged using advanced fluorescence microscopy techniques (bottom panel). Unlike current tissue clearing solutions, the Ce3D tissue clearing solution is robustly compatible...

Published: 7/25/2024 | Inventor(s): Michael Gerner, Weizhe Li, Ronald Germain

Keywords(s): 3D, AA3AXX, Ce3D:, Cellular, Clearing, Epitope, Fluorescence, histo-cytometry, IMAGING, imaging agent, Method, MICROSCOPY, REPORTER, Tissue

Category(s): Collaboration Sought > Collaboration

Microfabricated Particles Useful as MRI Contrast Agents

MRI contrast agents are versatile yet lack the sensitivity and multiplexing capabilities of optical agents. Available for licensing is an invention pertaining to microfabricated structures that can be used as MRI contrast agents with enhanced functionality or as micro-RFID (radio-frequency identification) tags. The microstructures can be engineered...

Published: 7/19/2024 | Inventor(s): Stephen Dodd, Alan Koretsky, John Moreland, Gary Zabow

Keywords(s): AA1XXX, AA3CXX, AA3XXX, AAXXXX, AB3CXX, AB3XXX, ABXXXX, AXXXXX, IMAGING, imaging agent, ImagingMRI, Magnetic, Magnetic Resonance, Microstructures, MRI, Resonance, STENT, Stents, SYSTEMS

Category(s): Collaboration Sought > Collaboration