Search Results - ronald+germain

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Enhanced Tissue Clearing Solution, Clearing-Enhanced 3D (Ce3D), Compatible with Advanced Fluorescence Microscopy Imaging

NIH immunologists have created a solution, Clearing-enhanced 3D (Ce3D), that can be used to make entire organs extremely transparent (top right panel). This allows the tissue to be imaged using advanced fluorescence microscopy techniques (bottom panel). Unlike current tissue clearing solutions, the Ce3D tissue clearing solution is robustly compatible...

Published: 7/25/2024 | Inventor(s): Michael Gerner, Weizhe Li, Ronald Germain

Keywords(s): 3D, AA3AXX, Ce3D:, Cellular, Clearing, Epitope, Fluorescence, histo-cytometry, IMAGING, imaging agent, Method, MICROSCOPY, REPORTER, Tissue

Category(s): Collaboration Sought > Collaboration

Hybridoma Cell Line D8H21, Monoclonal Antibody to the Specific Peptide-MHC Class II Complex

Hybridoma Cell Line D8H21, as described in Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13856-61 and developed in the laboratory of Dr. Ronald Germain.

Published: 7/25/2024 | Inventor(s): Ronald Germain

Keywords(s): Cell, D8H21, Hybridoma, Line, Listed LPM Hastings as of 4/15/2015, Mab, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RM, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Hybridoma Cell Line B6GE1, Monoclonal Antibody to the Specific Peptide-MHC Class II Complex

Hybridoma Cell Line B6GE1 as described in Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13856-61 and developed in the laboratory of Dr. Ronald Germain.

Published: 7/25/2024 | Inventor(s): Ronald Germain

Keywords(s): B6GE1, Cell, Hybridoma, Line, Mab, RM, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Hybridoma Cell Line 25-D1.16 Producing Monoclonal Anti-H-2Kb/SIINFEKL Complex Antibody

An H-2Kb/OVA hybridoma cell line producing a monoclonal antibody specific for the H-2Kb/SIINFEKL complex (clone 25-D1.16) as described in Immunity 1997 Jun;6(6):715-26 and developed in the laboratory of Dr. Ronald Germain at the National Institute of Allergy and Infectious Diseases.

Published: 7/25/2024 | Inventor(s): Angel Porgador, Ronald Germain

Keywords(s): 25-D1.16, Cell, Hybridoma, Line, Listed LPM Ano as of 4/15/2015, Mab, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RM, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Hybridoma C4H3, Monoclonal Antibody to a Specific Peptide-MHC Class II Complex

T lymphocytes play an important role in the immune system by recognizing foreign protein motifs on cells. T lymphocytes are stimulated to recognize these motifs through their interactions with peptide-MHC complexes (pMHC). Thus, studying pMHC is an important aspect of understanding how the immune system works, particularly with regard to the development...

Published: 7/25/2024 | Inventor(s): Ronald Germain

Keywords(s): ANTIBODY, CA1BXX, CA1XXX, CA2AXX, CA2XXX, CAXXXX, Class, COMPLEX, CXXXXX, Hybridoma, Mab, monoclonal, Peptide-MHC, RM, Specific, WIXXXX, XAXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies

Multi-Photon Microscopy System Configured for Multiview Non-Linear Optical Imaging

This invention is a microscopy device and system for multi-photon microscopy utilizing multi-view nonlinear optical imaging. Nonlinear optical imaging remains the premier technique for deep-tissue imaging in which typically a multi photon arrangement may be used to illuminate and excite a sample. However, the penetration depth, signal-to-noise ratio,...

Published: 7/25/2024 | Inventor(s): Ronald Germain, Jianyong Tang, Hari Shroff, Yicong Wu

Keywords(s): AC3XXX, ADXXXX, IMAGING, MICRSCOPY, Multiview, NONLINEAR, optical, RESOLUTION

Category(s): Collaboration Sought > Licensing