Search Results - resolution

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Resolution Enhancement for Line-Scanning Excitation Microscopy

The invention describes a method for improving the spatial resolution of optical microscopes that use line-scanning excitation, such as line-scanning confocal microscopes, line-scanning STED microscopes, or line-scanning light-sheet microscopes. Common elements of the invention include: a) an apparatus for exciting and scanning a line-like excitation...

Published: 10/28/2024 | Inventor(s): Andrew York, John Giannini, Abhishek Kumar, Hari Shroff

Keywords(s): AC1XXX, AC2XXX, AC3XXX, fluorescent, MICROSCOPE, MICROSCOPY, RESOLUTION, XDXXXX, XFXXXX, YFXXXX

Category(s): Collaboration Sought > Collaboration, Application > Software / Apps, Application > Non-Medical Devices, Application > Medical Devices, Application > Diagnostics

Rapid Detection of Multi-Drug-Resistant Mycobacterium tuberculosis Using Real-Time PCR and High-Resolution Melt Analysis

CDC scientists have developed a rapid, sensitive, and specific real-time PCR assay that is capable of detecting the presence of Mycobacterium tuberculosis and determining its resistance profile to antibiotics, such as rifampicin and isoniazid. Currently, there are few assays available that are capable of both detecting M. tuberculosis and determining...

Published: 10/28/2024 | Inventor(s): Jonas Winchell, Kelley Cowart, Melissa Ramirez, James Posey

Keywords(s): analysis, DA3XXX, DAXXXX, Detection, DXXXXX, High, Melt, Multidrug, PCR, PROCESS, REAL-TIME, RESISTANT, RESOLUTION, TUBERCULOSIS, Tuberculosis (Mycobacterium tuberculosis)

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics

Software to Improve the Quality of Microscopy Images

Available for licensing and commercial use is software based on an iterative deconvolution procedure that recovers images that have been blurred by a known point spread function. The software provides superior results when multiple independent observations of the same specimen are obtained. An example of such observations might be the multiple views...

Published: 4/8/2024 | Inventor(s): Andrew York, Yicong Wu, Hari Shroff

Keywords(s): AC2XXX, AC3XXX, ACXXXX, AD1XXX, ADXXXX, AXXXXX, Deconvolution, image quality, IMAGING, MICROSCOPY, RESOLUTION, Signal-to-Noise, software

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Multi-Photon Microscopy System Configured for Multiview Non-Linear Optical Imaging

This invention is a microscopy device and system for multi-photon microscopy utilizing multi-view nonlinear optical imaging. Nonlinear optical imaging remains the premier technique for deep-tissue imaging in which typically a multi photon arrangement may be used to illuminate and excite a sample. However, the penetration depth, signal-to-noise ratio,...

Published: 10/28/2024 | Inventor(s): Ronald Germain, Jianyong Tang, Hari Shroff, Yicong Wu

Keywords(s): AC3XXX, ADXXXX, IMAGING, MICRSCOPY, Multiview, NONLINEAR, optical, RESOLUTION

Category(s): Collaboration Sought > Licensing