Search Results - software

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Software System for Analysis of Extremely Large Experimental Dataset and Multidimensional Drug Discovery

Abstract: The National Institute on Aging, Laboratory of Neurosciences-Receptor Pharmacology Unit is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize biomedical informatics. This invention is a computer software suite that will enable its user to investigate...

Published: 7/25/2024 | Inventor(s): Stuart Maudsley, Tie Yi, Bronwen Martin

Keywords(s): gene arrays, proteomics, RESEARCH TOOL, software

Category(s): Application > Research Materials, Collaboration Sought > Licensing

Eye Tracking Application in Computer Aided Diagnosis and Image Processing in Radiology

Abstract: Medical imaging is an important resource for early diagnostic, detection, and effective treatment of cancers. However, the screening and review processes for radiologists have been shown to overlook a certain percentage of potentially cancerous image features. Such review errors may result in misdiagnosis and failure to identify tumors. These...

Published: 4/8/2024 | Inventor(s): Bradford Wood, Haydar Celik, Ulas Bagci, Ismail Turkbey

Keywords(s): CAD, cc, Clinical Center, Computer Aided Diagnostics, DEVICE, Eye tracking, Image Processing, National Institutes of Health, NIH, Radiology, software, WOOD

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Cardiology, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology

Biomarker Analysis Software for High-Throughput Diagnostic Multiplex Data

Abstract: Extracellular vesicles (EVs) are lipid bilayer-enclosed particles that are released from cells. EVs may contain proteins derived from their cells of origin with the potential as diagnostic biomarkers indicating the state of the cells when released. However, due to their small size (50-1000nm), the methods currently used to phenotype EVs have...

Published: 8/14/2024 | Inventor(s): Joshua Welsh, Jennifer Jones, Jay Berzofsky

Keywords(s): Berzofsky, Biomarker, EV, Extracellular Vesicles, High-throughput, Jones, Lipid Bilayer-Enclosed Particles, software

Category(s): Application > Software / Apps, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

NIMH DAO Toolbox: Data acquisition software that enables real-time sample analysis

This technology relates to a software package called NIMH DAO Toolbox that uses multithreading and a unique buffer structure to shorten gaps in sample readouts. Data acquisition devices running in continuous sampling mode collect data samples at a given sampling rate. The samples are typically stored in a memory buffer and read out at a regular interval....

Published: 7/25/2024 | Inventor(s): Jaewon Hwang

Keywords(s): 3FXXXX, 4FXXXX, Acquisition, analysis, DAO, DATA, NIMH, REAL-TIME, SAMPLE, SIMULTANEOUSLY, software, Toolbox:, VPXXXX, WEXXXX, WMXXXX, XBXXXX, XHXXXX, XJXXXX

Category(s): Application > Occupational Safety and Health, Application > Software / Apps, ResearchProducts > Research Equipment, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology

Novel Codon-Optimized MUT Gene Therapeutic for Methylmalonic Acidemia (MMA)

Methylmalonic Acidemia (MMA) is a metabolic disorder characterized by increased acidity in the blood and tissues due to toxic accumulation of protein and fat by-products resulting in seizures, strokes, and chronic kidney failure. A significant portion of MMA cases stem from a deficiency in a key mitochondrial enzyme, methylmalonyl-CoA mutase (MUT),...

Published: 7/25/2024 | Inventor(s): Colin Shea, Ciprian Crainiceanu, Elizabeth Sweeney, Russell Shinohara, Arthur Goldsmith, Daniel Reich

Keywords(s): Automatic, brain, Detection, IMAGING, Incidence, Lesion, Listed LPM Shmilovich as of 4/15/2015, Longitudinal, Magnetic, MULTIMODALITY, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Resonance, software, SuBLIME:, VPXXXX, WJXXXX, XEXXXX

Category(s): TherapeuticArea > Cardiology, TherapeuticArea > Oncology, TherapeuticArea > Ophthalmology, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease

OASIS: Automated brain lesion detection using cross-sectional multimodal magnetic resonance imaging

This invention is a novel statistical method for automatically detecting lesions in cross-sectional brain magnetic resonance imaging (MRI) studies. OASIS uses multimodal MRI from one image acquisition session and produces voxel-level probability maps of the brain that quantifies the likelihood that each voxel is part of a lesion. Binary lesion segmentations...

Published: 7/25/2024 | Inventor(s): Ciprian Crainiceanu, Elizabeth Sweeney, Russell Shinohara, Arthur Goldsmith, Navid Shiee, Dzung Pham, Daniel Reich

Keywords(s): Automated, brain, CNRM CRADA, Cross, Detection, IMAGING, Lesion, Listed LPM Shmilovich as of 4/15/2015, Magnetic, MULTIMODALITY, OASIS:, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Resonance, SECTIONAL, software, VEXXXX, WBXXXX, WIXXXX, XFXXXX

Category(s): Collaboration Sought > Licensing, Application > Medical Devices, Application > Research Materials, Application > Software / Apps, Application > Diagnostics, Application > Non-Medical Devices, TherapeuticArea > Neurology

Software to Improve the Quality of Microscopy Images

Available for licensing and commercial use is software based on an iterative deconvolution procedure that recovers images that have been blurred by a known point spread function. The software provides superior results when multiple independent observations of the same specimen are obtained. An example of such observations might be the multiple views...

Published: 4/8/2024 | Inventor(s): Andrew York, Yicong Wu, Hari Shroff

Keywords(s): AC2XXX, AC3XXX, ACXXXX, AD1XXX, ADXXXX, AXXXXX, Deconvolution, image quality, IMAGING, MICROSCOPY, RESOLUTION, Signal-to-Noise, software

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Image Analysis Software for Quantitative Evaluation of Striation Patterns and their Defects in Skeletal Muscles

Available for licensing is software written in MatLab for evaluating striation patters in images of skeletal muscle fibers for better sensitivity in the quantitation of skeletal muscle disorders. Skeletal muscles have a regular, periodic organization (the periodicity of the sarcomeres), which is not only structural but also functional. Muscle pathologies...

Published: 7/30/2024 | Inventor(s): Evelyn Ralston, Wenhua Liu

Keywords(s): AD1XXX, AD3XXX, ADXXXX, AXXXXX, MATLAB, MATLAB-based, RESEARCH TOOL, Skeletal Muscle, software

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Software System for Processing and Analysis of Multi-dimensional NMR Data

Available for licensing is a software system useful in applications involving nuclear magnetic resonance (NMR). The software system, called NMRPipe, is written in the C programming language, and makes use of the TCL/TK scripting environment. The system includes over 500 modules for processing and analyzing experimental data of one to four dimensions...

Published: 7/25/2024 | Inventor(s): Frank Delaglio

Keywords(s): ADXXXX, analysis, AXXXXX, DATA, Multi-dimensional, NMR, NMRPipe, Processing, software, System

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Interactive Venn Diagram Software Designed for Microarray Analysis

Multiple conditions from any source, but designed for experiments involving microarrays, will produce (significant gene lists for arrays) lists from each condition, thus multiple lists. This Java® based software provides investigators with a method of displaying multiple conditions in a single graphic along with producing a text output of genes that...

Published: 7/25/2024 | Inventor(s): Daniel Sturdevant

Keywords(s): AD1XXX, AD3XXX, ADXXXX, AXXXXX, Bioinformatic, Bioinformatics, Genomic, Genomics, Java, Java-based, microarray, MICROARRAYS, software, Venn, Venn Diagram

Category(s): Collaboration Sought > Licensing

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