Search Results - high-throughput

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Automatic System and Method for Tissue Sectioning, Staining, and Scanning

Abstract: Computer and imaging technologies led to the development of digital pathology and the capture and storage of pathological specimens as digitally formatted images. The use of artificial intelligence (AI) in digital pathology, such as in three-dimensional (3D) reconstruction, requires analyses of high volumes of data. This results in increased...

Published: 4/8/2024 | Inventor(s): Zhengping (Ping) Zhuang, Young-Wan Moon

Keywords(s): AI, Artificial Intelligence, AUTOMATION, Digital Pathology, High-throughput, Histology, IMAGING, Zhuang

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Neurology, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Non-Medical Devices

Exo-Clean Technology for Purifying Extracellular Vesicle Preparations from Contaminants

Abstract: Extracellular Vesicles (EVs), including exosomes and microvesicles, are nanometer-sized membranous vesicles that can carry different types of cargos, such as proteins, nucleic acids and metabolites. EVs are produced and released by most cell types. They act as biological mediators for intercellular communication via delivery of their cargos....

Published: 8/14/2024 | Inventor(s): Jennifer Jones, Jay Berzofsky, Joshua Welsh, Katherine McKinnon

Keywords(s): Affinity, Biomarkers, CHROMATOGRAPHIC, EVs, Exo-Clean, Exosomes, Extracellular Vesicles, High-throughput, Jones, Microvesicles, purification, Resin

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Endocrinology, TherapeuticArea > Immunology

Biomarker Analysis Software for High-Throughput Diagnostic Multiplex Data

Abstract: Extracellular vesicles (EVs) are lipid bilayer-enclosed particles that are released from cells. EVs may contain proteins derived from their cells of origin with the potential as diagnostic biomarkers indicating the state of the cells when released. However, due to their small size (50-1000nm), the methods currently used to phenotype EVs have...

Published: 8/14/2024 | Inventor(s): Joshua Welsh, Jennifer Jones, Jay Berzofsky

Keywords(s): Berzofsky, Biomarker, EV, Extracellular Vesicles, High-throughput, Jones, Lipid Bilayer-Enclosed Particles, software

Category(s): Application > Software / Apps, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Automated Digital Pathology Device for High-Throughput Demand

Published: 4/8/2024 | Inventor(s): Zhengping (Ping) Zhuang, Young-Wan Moon, Anthony Cappadona

Keywords(s): AI, Artificial Intelligence, AUTOMATION, Digital Pathology, High-throughput, Histology, IMAGING, Zhuang

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Medical Devices, TherapeuticArea > Oncology

Cotranslational Protein Expression System for High-throughput Screening

Reporter gene-based assays are used extensively in high-throughput screening (HTS) to identify chemical modulators of cellular pathways for drug discovery and development. However, such screening frequently results in a large number of false “hits” due to interactions of screened compounds with reporter proteins, producing confounding results. Thus,...

Published: 7/25/2024 | Inventor(s): Chih-Chien (Ken) Cheng, Samuel Hasson, James Inglese

Keywords(s): AC4XXX, ACXXXX, AXXXXX, Coincidence, drug discovery, Drug Screening, High-throughput, High-throughput screen, HTS, REPORTER, reporter gene

Category(s): Collaboration Sought > Collaboration