Search Results - jonas+winchell

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Real-time PCR and High Resolution Melt Analysis for Genotyping of Chlamydophila psittaci

This nucleic acid assay employs Light Upon Extension (LUX) chemistry and High Resolution Melt (HRM) analysis to detect and distinguish the different genotypes of Chlamydophila psittaci. C. psittaci is an atypical pathogen which may result in severe pneumonia upon infection of birds, mammals and humans (depending on inter-relationships between host...

Published: 7/25/2024 | Inventor(s): Jonas Winchell, Stephanie Mitchell

Keywords(s): Acids, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chlamydophila, DA3XXX, DAXXXX, Detection, discrimination, DXXXXX, GENOTYPES, Nucleic, OID-NCIRD-DBD, PSITTACI, VJXXXX, VOXXXX, WBXXXX, WCXXXX, WFXXXX, WHXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Therapeutics

Real-time PCR Multiplex Assay for Detection of Bacterial Respiratory Pathogens in Clinical Specimens

CDC researchers have developed a single-tube, real-time PCR assay for the simultaneous detection of three bacterial respiratory pathogens (Mycoplasma pneumoniae, Chlamydiophila pneumoniae and Legionella spp.). The assay has an internal control testing for presence of human DNA. This four-plex real-time PCR assay could potentially become a routine screening...

Published: 7/25/2024 | Inventor(s): Agnes Warner, Kathleen Thurman, Jonas Winchell

Keywords(s): AA5XXX, AAXXXX, assay, AXXXXX, Bacterial, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, DXXXXX, Multiplex, OID-NCIRD-DBD, PATHOGENS, PCR, REAL, respiratory, TIME

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease

Multiplex Real-time PCR Assay for Detection of Numerous Bacterial Pathogens

In order to address a global need for rapid, cost-effective, sensitive, and specific assays for many pathogens, CDC scientists have developed a broad-use, multiplexed RT-PCR assay. This comprehensive assay covers numerous pathogens that are common causes of infection in neonates and also important to food-safety. Specifically, this assay (and respective...

Published: 7/25/2024 | Inventor(s): Bernard Wolff, Maureen Diaz, Jonas Winchell

Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, DXXXXX, PATHOGENS, PCR, REAL-TIME

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics

Rapid Detection of Multi-Drug-Resistant Mycobacterium tuberculosis Using Real-Time PCR and High-Resolution Melt Analysis

CDC scientists have developed a rapid, sensitive, and specific real-time PCR assay that is capable of detecting the presence of Mycobacterium tuberculosis and determining its resistance profile to antibiotics, such as rifampicin and isoniazid. Currently, there are few assays available that are capable of both detecting M. tuberculosis and determining...

Published: 7/25/2024 | Inventor(s): Jonas Winchell, Kelley Cowart, Melissa Ramirez, James Posey

Keywords(s): analysis, DA3XXX, DAXXXX, Detection, DXXXXX, High, Melt, Multidrug, PCR, PROCESS, REAL-TIME, RESISTANT, RESOLUTION, TUBERCULOSIS, Tuberculosis (Mycobacterium tuberculosis)

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics

Simultaneous Detection of Non-pneumophila Legionella Strains Using Real-time PCR

Legionnaires' disease is caused by a type of bacteria called Legionella. CDC scientists have developed a real-time multiplex PCR assay for diagnosis and identification of Legionella strains. The assay consists of five sets of primers (targeting L. bozemanii, L. dumoffii, L. feeleii, L. longbeachae, or L. micdadei) and corresponding probes. Each probe...

Published: 7/25/2024 | Inventor(s): Alvaro Benitez, Jonas Winchell

Keywords(s): Compositions, DA3XXX, DAXXXX, Detection, DXXXXX, LEGIONELLA, Methods

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease