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Sensor for Real-time Detection of Plasma Metabolites Levels for the Diagnosis and Care of Metabolic Disorders
This technology includes the development of devices capable of real-time evaluation of metabolite levels for the treatment of numerous metabolic disorders, including hyperammonemia and aminoacidopathies. Currently, the monitoring of metabolite levels is done in a hospital setting with specialized mass spectrometry instrumentation. As a consequence,...
Published: 7/25/2024   |   Inventor(s): Adam Behrens, Peter Kofinas, Marshell Summar, Juan Luque-Cabrera, Gary Cunningham, Juan Marugan, Anton Simeonov, Omar Ayyub
Keywords(s): Detection, DEVICE, Listed LPM Tong as of 4/15/2015, MECHANICAL, METABOLITES, Metabolites., PLASMA, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, REAL, SENSOR, TIME, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XDXXXX
Category(s): TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Diagnostics, Application > Occupational Safety and Health, Application > Research Materials
Real-time RT-PCR Assay For Detection and Quantification of Hepatitis D Virus Infection
CDC scientists have developed a one-step TaqMan quantitative/real-time reverse transcription-polymerase chain reaction (qRT-PCR) assay for detecting hepatitis D virus (HDV) RNA. Additionally, a quantifiable synthetic RNA control to determine viral load has been created. HDV is an operatively defective virus that requires hepatitis B virus (HBV) surface...
Published: 7/25/2024   |   Inventor(s): Tonya Mixson-Hayden, Saleem Kamili, Maja Kodani
Keywords(s): assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, cirrhosis, D, DA4BXX, DA4XXX, DAXXXX, Detection, diagnostic, Diagnostic assay, DXXXXX, HBV, HDV, Hepatitis, HEPATITIS B, liver, liver disease, Liver disorders, Liver-Disease, OID-NCHHSTP-DVH, PCR, QUANTITATIVE, REAL, real time, REAL-TIME, RT-PCR, viral, virus
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease
Real-time PCR Multiplex Assay for Detection of Bacterial Respiratory Pathogens in Clinical Specimens
CDC researchers have developed a single-tube, real-time PCR assay for the simultaneous detection of three bacterial respiratory pathogens (Mycoplasma pneumoniae, Chlamydiophila pneumoniae and Legionella spp.). The assay has an internal control testing for presence of human DNA. This four-plex real-time PCR assay could potentially become a routine screening...
Published: 7/25/2024   |   Inventor(s): Agnes Warner, Kathleen Thurman, Jonas Winchell
Keywords(s): AA5XXX, AAXXXX, assay, AXXXXX, Bacterial, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, DXXXXX, Multiplex, OID-NCIRD-DBD, PATHOGENS, PCR, REAL, respiratory, TIME
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease
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