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Real-time PCR Assays for Human Bocavirus Detection and Diagnosis

CDC researchers have developed a real-time PCR assay for the detection and viral-load quantitative estimations of human bocavirus (HBoV) from clinical specimens. At present, there have been few reports on the epidemiology, geographic distribution or clinical features of HBoV infection. Additionally, symptoms affiliated with bocavirus infections overlap...

Published: 4/8/2024 | Inventor(s): Teresa Peret, Dean Erdman

Keywords(s): Bocavirus, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4XXX, DAXXXX, DXXXXX, Human, NAT, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, OID-NCIRD-DVD, Processes, QUANTITATIVE, real time, Realtime, REAL-TIME, Relating, respiratory, Respiratory Diseases, respiratory INFECTION, viral, VIRAL DIAGNOSTIC, VLXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Dental, Application > Diagnostics, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Oncology

Real-time RT-PCR Assay for the Detection of Rift Valley Fever Virus in Humans and Livestock

A quantitative RT-PCR-based assay has been developed to rapidly detect all known strains of Rift Valley fever virus (RVFV). RVFV infections occur in both humans and livestock animals resulting in significant mortality and economic loss. Upon outbreak, RVFV has been known to cause devastating loss among livestock (primarily sheep and cattle) with outbreaks...

Published: 7/25/2024 | Inventor(s): Stuart Nichol, Brian Bird

Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DDXXXX, Diagnosis, DXXXXX, FEVER, Kits, Methods, Pan-Rift, QUANTITATIVE, REAL-TIME, RT-PCR, Valley, VBXXXX, virus, VLXXXX, VOXXXX, WAXXXX, WDXXXX, WFXXXX, WIXXXX, WMXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Vaccines, Application > Therapeutics

Real-time RT-PCR Assay For Detection and Quantification of Hepatitis D Virus Infection

CDC scientists have developed a one-step TaqMan quantitative/real-time reverse transcription-polymerase chain reaction (qRT-PCR) assay for detecting hepatitis D virus (HDV) RNA. Additionally, a quantifiable synthetic RNA control to determine viral load has been created. HDV is an operatively defective virus that requires hepatitis B virus (HBV) surface...

Published: 7/25/2024 | Inventor(s): Tonya Mixson-Hayden, Saleem Kamili, Maja Kodani

Keywords(s): assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, cirrhosis, D, DA4BXX, DA4XXX, DAXXXX, Detection, diagnostic, Diagnostic assay, DXXXXX, HBV, HDV, Hepatitis, HEPATITIS B, liver, liver disease, Liver disorders, Liver-Disease, OID-NCHHSTP-DVH, PCR, QUANTITATIVE, REAL, real time, REAL-TIME, RT-PCR, viral, virus

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease

Modified Peptide Nucleic Acids (PNAs) for Detection of DNA or RNA and Identification of a Disease or Pathogen

The NIH announces a novel method for fast, simple, and accurate detection of nucleic acids outside the modern laboratory. Nucleic acid testing is highly specific and often provides definitive identification of a disease or pathogen. Methods to detect nucleic acid sequences and identify a disease or pathogen are dominated by PCR, but applying PCR-based...

Published: 7/25/2024 | Inventor(s): Christopher Micklitsch, Bereket Yemane (formerly Oquare), Chao Zhao, Daniel Appella

Keywords(s): Acids, Cyclopentane-Peptide, DAXXXX, Detection, DXXXXX, Nucleic, Qualitative, QUANTITATIVE, YXXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Infectious Disease

Simple, Quantitative Sensitive High-throughput Antibody Detection for Lyme Disease

This technology is for compositions and methods for diagnosis of Lyme disease. Currently, Lyme disease is diagnosed by clinical exam and a history of exposure to endemic regions. Although, laboratory tests may aid diagnosis, the best tests currently available are slow and labor intensive and require understanding of the test, and infection stage....

Published: 7/25/2024 | Inventor(s): Adriana Marques, Michael Iadarola, Peter Burbelo

Keywords(s): ANTIBODY, Borreliosis, DAXXXX, Detection, Disease, DXXXXX, Highly, Listed LPM Fenn as of 4/15/2015, LYME, Lyme Disease, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, QUANTITATIVE, SENSITIVE, SIMPLE, VJXXXX, WBXXXX

Category(s): TherapeuticArea > Infectious Disease, Application > Diagnostics