Search Results - acids

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Real-time PCR and High Resolution Melt Analysis for Genotyping of Chlamydophila psittaci

This nucleic acid assay employs Light Upon Extension (LUX) chemistry and High Resolution Melt (HRM) analysis to detect and distinguish the different genotypes of Chlamydophila psittaci. C. psittaci is an atypical pathogen which may result in severe pneumonia upon infection of birds, mammals and humans (depending on inter-relationships between host...

Published: 7/25/2024 | Inventor(s): Jonas Winchell, Stephanie Mitchell

Keywords(s): Acids, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chlamydophila, DA3XXX, DAXXXX, Detection, discrimination, DXXXXX, GENOTYPES, Nucleic, OID-NCIRD-DBD, PSITTACI, VJXXXX, VOXXXX, WBXXXX, WCXXXX, WFXXXX, WHXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Therapeutics

Nucleic Acid-based Differentiation and Identification of Medically Important Fungi

This invention, entailsnucleic acid-based assays, for detecting the presence of pathogenic fungi such as Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Pneumocystis brasiliensis, and/or Penicillium marneffei within a sample. Within a healthcare setting, this particular approach can greatly reduce pathogen identification time,...

Published: 7/25/2024 | Inventor(s): Zhenyu Qin, Jong Soo Choi, Christine Morrison, Mark Lindsley

Keywords(s): Acids, AIDS, Aspergilli, Aspergillus, CAPSULATUM, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, Detection, diagnostic, DXXXXX, FUNGAL, FUNGI, fungus, HIV, Identification, Methods, Mold, Molds, Nucleic, OID-NCEZID-DFWED, PCR, Probe, Probes, SAME, SECONDARY, secondary infection, thrush, VKXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Research Materials, ResearchProducts > Research Equipment, Application > Diagnostics, TherapeuticArea > Ophthalmology, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease

Species-specific Nucleic Acid Detection Assay for Fungi

This invention pertains to nucleic acid-based assays for the detection of Aspergillus and other filamentous fungi. Assays cover the species-specific detection and diagnosis of infection by Aspergillus, Fusarium, Mucor, Penecillium, Rhizomucor, Absidia, Cunninghamella, Pseudallescheria or Sporthrix in a subject. This can reduce identification time from...

Published: 7/25/2024 | Inventor(s): Errol Reiss, Lilianna Aidorevich, Jong Soo Choi, Christine Morrison

Keywords(s): Acids, Aspergillus, CANDIDA, CANDIDA ALBICANS, candidiasis, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, Detection, diagnostic, discrimination, DXXXXX, FUNGAL, FUNGI, fungus, I-016-96, I-016-96/0, Mold, Molds, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, OID-NCEZID-DFWED, PCR, PCR ASSAY, PRIMERS, Species, VKXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology

Nucleic Acid Amplification Technique for Rapid Diagnostic Analysis

CDC researchers developed a simple target-specific isothermal nucleic acid amplification technique, termed Genome Exponential Amplification Reaction (GEAR). The method employs a set of four primers (two inner and two outer). The outer primer pair targets three specific nucleic acid sequences at a constant 60°C, while the inner pair of primers accelerates...

Published: 7/25/2024 | Inventor(s): Prithiviraj Jothikumar, Vincent Hill, Jothikumar Narayanan

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, Acids, ACXXXX, amplification, AMPLIFYING, AXXXXX, DA1XXX, DA2XXX, DA3XXX, DA4XXX, DA5XXX, DAXXXX, DXXXXX, Exponential, Gear, Genome, Isothermal, Methods, Nucleic, REACTION, REAGENTS, UBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Rare / Neglected Diseases, TherapeuticArea > Infectious Disease, Application > Diagnostics

Modified Peptide Nucleic Acids (PNAs) for Detection of DNA or RNA and Identification of a Disease or Pathogen

The NIH announces a novel method for fast, simple, and accurate detection of nucleic acids outside the modern laboratory. Nucleic acid testing is highly specific and often provides definitive identification of a disease or pathogen. Methods to detect nucleic acid sequences and identify a disease or pathogen are dominated by PCR, but applying PCR-based...

Published: 7/25/2024 | Inventor(s): Christopher Micklitsch, Bereket Yemane (formerly Oquare), Chao Zhao, Daniel Appella

Keywords(s): Acids, Cyclopentane-Peptide, DAXXXX, Detection, DXXXXX, Nucleic, Qualitative, QUANTITATIVE, YXXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Infectious Disease

Use of Modified Peptide Nucleic Acids for Visualizing DNA

The compounds described in this technology may be useful in the development of nucleic acid detection kits for various pathogens. Technologies for genomic detection most commonly use DNA probes to hybridize to target sequences, and require the use of Polymerase Chain Reaction (PCR) to amplify target sequences. Replacing the DNA probe with peptide nucleic...

Published: 7/25/2024 | Inventor(s): Daniel Appella

Keywords(s): 2, Acid, Acids, Anthrax, APPLICATIONS, Cross-Coupled, Cyclopentan, Detection, Diamine-modified, Gamma-lysine, Modified, Nucleic, Patent Category - Chemistry, PATHOGENS, Peptide, Probes, SARS, Severe acute respiratory syndrome, Synthesis, Trans-1, YXXXXX

Category(s): Collaboration Sought > Collaboration