Search Results - detecting

11 Results

Sort By:

Nucleic Acid Primers and Probes for Detecting Ebola Virus (species Zaire ebolavirus)

The 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa was the largest in history, causing more than 28,000 suspected, probable, and confirmed infections and more than 11,000 deaths across nine countries. CDC scientists designed nucleic acid primers and probes which can be used in a sensitive test for detecting all known strains of Ebola virus...

Published: 7/25/2024 | Inventor(s): Tara Sealy, Ute Stroeher, Stuart Nichol, Jonathan Towner

Keywords(s): 7, Acid, antibodies, ANTIGENS, assay, DETECTING, Detection, Ebola, Ebolavirus, ELISA, Enzyme, Identification, immunosorbent, LINKED, Listed LPM Kirby as of 4/15/2015, Mab, monoclonal, Mouse, NCEZID, NCEZID-DHCPP, Nucleic, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMERS, Probes, Species, Used, virus, Viruses, Zaire

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Recombinant Polypeptides for Clinical Detection of Taenia solium and Diagnosis of Cysticercosis

CDC scientists have developed synthetic/recombinant polypeptides that can be used for the creation of inexpensive, high-quality cysticercosis diagnostic assays. Taenia solium is a species of pathogenic tapeworm. Intestinal infection with this parasite is referred to as taeniasis and it is acquired by ingestion of T. solium cysticerci found in raw...

Published: 7/25/2024 | Inventor(s): Ryan Greene, Patricia Wilkins, Kathy Hancock, Victor Tsang

Keywords(s): ANTIGEN, CDC Docket Import, CDC Docket Import CDC Prosecuting, CGH-DPDM, Cloned, Compositions, DA2XXX, DAXXXX, DETECTING, diagnostic, DXXXXX, I-031-98, I-031-99, Larval, Methods, SOLIUM, TAENIA, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WJXXXX, WMXXXX, XAXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Diagnostics, ResearchProducts > Antibodies, Application > Research Materials, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, TherapeuticArea > Oncology

Enterovirus Molecular Diagnostic Test Kit

CDC researchers have developed a reverse transcription/semi-nested polymerase chain reaction (RT-snPCR) assay for diagnosis of enterovirus infections within clinical specimens. Clinical laboratories currently identify enteroviruses by virus isolation and subsequent virus neutralization tests, or serological assays. In addition to being time consuming,...

Published: 7/25/2024 | Inventor(s): Mark Oberste, William Nix

Keywords(s): Acid, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4BXX, DA4XXX, DAXXXX, DETECTING, DXXXXX, Enteroviruses, Identifying, Including, Kits, MOLECULES, Nucleic, OID-NCIRD-DVD, USEFUL, VLXXXX, VOXXXX, VP1, VP3, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Occupational Safety and Health, Application > Research Materials, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Therapeutics

Simple, Rapid, and Sensitive Real-Time PCR Assays for Detecting Drug Resistance of HIV

This novel assay features real-time PCR reagents and methods for detecting drug-resistance related mutations in HIV, for newly diagnosed patients and those individuals currently receiving antiretroviral therapies. As the use of antiretroviral compounds to treat HIV infection proliferates, viruses adapt and evolve mutations limiting the efficacy of...

Published: 7/25/2024 | Inventor(s): Jonathan Lipscomb, Walid Heneine, Jeffrey Johnson

Keywords(s): 1, ANTIVIRAL, Anti-Viral, ASSAYS, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4XXX, DAXXXX, DETECTING, DRUGS, DXXXXX, HIV, HIV-1, Listed LPM Houze as of 4/15/2015, MUTATION, NCHHSTP-DHPSE, OID-NCHHSTP-DHPSE, PCR, POINT, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, REAL-TIME, Resistance, VLXXXX, VPXXXX, WBXXXX, WFXXXX, XBXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, Application > Occupational Safety and Health, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology, Application > Research Materials, ResearchProducts > Computational models/software, Application > Consumer Products, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease

Rapid Detection of Antiretroviral(s) Drug-Resistant HIV-1 within Clinical Samples

One of the problems with the development of current therapies for HIV infection is that the virus rapidly develops resistance to drugs such as reverse transcriptase (RT) inhibitors. CDC researchers have developed an enzyme-based methodology for detecting phenotypic resistance to antiretroviral drugs whose mode of action decreases the efficiency of...

Published: 7/25/2024 | Inventor(s): Gerardo Lerma, Shinji Yamamoto, William Switzer, Thomas Folks, Walid Heneine

Keywords(s): ANTIVIRAL, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4XXX, DAXXXX, DB4AXX, DETECTING, DRUGS, DXXXXX, KIT, Method, OID-NCHHSTP-DHPSE, Resistance, VLXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Occupational Safety and Health, TherapeuticArea > Cardiology, Application > Diagnostics, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Therapeutics

Nucleic Acid-based Compositions and Methods for the Species-Specific Detection of Pathogenic Candida Fungi

This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of the Candida fungi species C. haemulonii, C. kefyr, C. lambica, C. lusitaniae, C. norvegensis, C. norvegica, C. rugosa, C. utilis, C. viswanathii, C. zeylanoides, C. dubliniensis, and C. pelliculosa within biological samples. This identification...

Published: 7/25/2024 | Inventor(s): Cheryl Elie, Christine Morrison, Errol Reiss, Timonthy Lott

Keywords(s): Acid, CANDIDA, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, DXXXXX, Nucleic, OID-NCEZID-DFWED, Probes, Species, VKXXXX, VOXXXX, VPXXXX, WBXXXX, WCXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, TherapeuticArea > Dental, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology

Nucleic Acid Detection of the Fungal Pathogen Histoplasma capsulatum from Clinical and Environmental Samples

This invention relates to detecting Histoplasma capsulatum by PCR using oligonucleotide probes specific for the fungus. Histoplasmosis is a mycotic infection of varying severity, usually localized in the lungs. Caused by H. capsulatum, infections are usually symptomatic but can develop into chronic disease, especially in immunocompromised individuals. Test...

Published: 7/25/2024 | Inventor(s): Thomas Reid, Millie Schafer

Keywords(s): AA5XXX, AAXXXX, AIDS, assay, Avian, AXXXXX, CAPSULATUM, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, Detection, diagnostic, DXXXXX, FUNGAL, FUNGI, fungus, HISTOPLASMA, Histoplasmosis, HIV, Method, NESTED, NIOSH-DART, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, PATHOGEN, PATHOGENIC, PATHOGENS, PCR, PCR ASSAY, RAPID, SENSITIVE, VKXXXX, VOXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XCXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX, Zoo, Zoonotic

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Infectious Disease, TherapeuticArea > Dental, TherapeuticArea > Oncology, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, Application > Therapeutics

Species-specific Nucleic Acid Detection Assay for Fungi

This invention pertains to nucleic acid-based assays for the detection of Aspergillus and other filamentous fungi. Assays cover the species-specific detection and diagnosis of infection by Aspergillus, Fusarium, Mucor, Penecillium, Rhizomucor, Absidia, Cunninghamella, Pseudallescheria or Sporthrix in a subject. This can reduce identification time from...

Published: 7/25/2024 | Inventor(s): Errol Reiss, Lilianna Aidorevich, Jong Soo Choi, Christine Morrison

Keywords(s): Acids, Aspergillus, CANDIDA, CANDIDA ALBICANS, candidiasis, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, Detection, diagnostic, discrimination, DXXXXX, FUNGAL, FUNGI, fungus, I-016-96, I-016-96/0, Mold, Molds, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, OID-NCEZID-DFWED, PCR, PCR ASSAY, PRIMERS, Species, VKXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology

Novel Recombinant Rabies Vaccine Also Capable of Immunocontraception

This invention relates to a recombinant, attenuated rabies vaccine that is also capable of inhibiting reproductive fertility. An Evelyn-Rokitnicki-Abelseth (ERA) rabies vaccine backbone, combined with a reproductive-specific protein, such as gonadotropin-releasing hormone (GnRH) or the sperm-binding zona-pellucida-glycoprotein-3 (ZP3) receptor, allows...

Published: 7/25/2024 | Inventor(s): Charles Rupprecht, Xianfu Wu

Keywords(s): AFXXXX, Agents, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DCXXXX, DETECTING, DEXXXX, DXXXXX, IMMUNOCONTRACEPTIVE, Methods, OID-NCEZID-DHCPP, OID-NCIRD-DVD, PARECHOVIRUS, rabies, recombinant, VIRUS-BASED

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines, Application > Diagnostics

Diagnostic Assays Utilizing Real-Time Taqman or Seminested RT-PCR for Parechovirus Detection and Discrimination

The CDC developed a real-time reverse transcription polymerase chain reaction (RT-PCR) Taqman assay and an RT-semi nested PCR (RT-snPCR) assay for the detection of parechoviruses. Similar to enteroviruses, parechoviruses are responsible for gastrointestinal, respiratory and central nervous system infections. All tests target conserved regions in the...

Published: 7/25/2024 | Inventor(s): Mark Oberste, William Nix

Keywords(s): Agents, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4BXX, DA4XXX, DAXXXX, DETECTING, DXXXXX, Methods, OID-NCIRD-DVD, PARECHOVIRUS

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease

1 2