Search Results - william+switzer

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A Diagnostic Kit for Assessing Exposure or Infection by the Koala Family of Retroviruses

This invention relates to a diagnostic kit for assessing exposure to or infection by a koala retrovirus. The kit consists of specific primers and probes for the detection of three distinct subtypes of infectious koala retrovirus and may be useful in various species, including humans, primates, and koalas. A family of infectious koala retroviruses are...

Published: 7/25/2024 | Inventor(s): Wenqin Xu, William Switzer, HaoQiang Zheng, Maribeth Eiden

Keywords(s): ASSESSING, CA1AXX, DA4BXX, diagnostic, Exposure, FAMILY, Gammaretroviruses, Infection, KIT, Koala, Listed LPM Maddox as of 4/15/2015, Ofgammaretroviruses, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, VCXXXX, VLXXXX, VOXXXX, WBXXXX, XCXXXX

Category(s): Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Research Materials

Multiple Antigenic Peptide Assays for Detection of HIV and SIV Type Retroviruses

CDC scientists have developed multiple antigenic peptide immunoassays for the detection of human immunodeficiency virus (HIV) and/or simian immunodeficiency virus (SIV). HIV can be subdivided into two major types, HIV-1 and HIV-2, both of which are believed to have originated as result of zoonotic transmission. Humans are increasingly exposed to...

Published: 7/25/2024 | Inventor(s): Clement Ndongmo, Chou-Pong Pau, William Switzer, Thomas Folks, Marcia Kalish

Keywords(s): ANTIGENIC, assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4BXX, DA4XXX, DAXXXX, DDXXXX, Detection, DXXXXX, HIV, MULTIPLE, OID-NCHHSTP-DHPSE, Peptide, Retroviruses, Serologic, SEROLOGICAL, SIV, TYPE, VLXXXX, VOXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Occupational Safety and Health, Application > Diagnostics, ResearchProducts > Antibodies, Application > Therapeutics

Detection of Retroviruses and HIV-1 Groups -M and -O Discrimination within Clinical Serum Samples

CDC researchers have developed methods for detecting retroviruses within a patient blood sample and discriminating HIV-1 samples within serum specimens. HIV-1 can be genetically classified into two major groups, group M (major) and Group O (outlier) with group O comprising all divergent viruses that do not cluster with group M. The identification of...

Published: 4/8/2024 | Inventor(s): Thomas Folks, Shinji Yamamoto, William Switzer, Walid Heneine

Keywords(s): Activity, assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4XXX, DAXXXX, Detection, DXXXXX, Methods, OID-NCHHSTP-DHPSE, Reverse, RT, SENSITIVE, TRANSCRIPTASE, VLXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Consumer Products

Rapid Detection of Antiretroviral(s) Drug-Resistant HIV-1 within Clinical Samples

One of the problems with the development of current therapies for HIV infection is that the virus rapidly develops resistance to drugs such as reverse transcriptase (RT) inhibitors. CDC researchers have developed an enzyme-based methodology for detecting phenotypic resistance to antiretroviral drugs whose mode of action decreases the efficiency of...

Published: 7/25/2024 | Inventor(s): Gerardo Lerma, Shinji Yamamoto, William Switzer, Thomas Folks, Walid Heneine

Keywords(s): ANTIVIRAL, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4XXX, DAXXXX, DB4AXX, DETECTING, DRUGS, DXXXXX, KIT, Method, OID-NCHHSTP-DHPSE, Resistance, VLXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Occupational Safety and Health, TherapeuticArea > Cardiology, Application > Diagnostics, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Therapeutics

Novel Primate T-cell Lymphotropic Viruses (HTLV, STLV) for Development of Diagnostics, Therapeutics, Research Tools, and Vaccines

CDC researchers have isolated and characterized the novel primate T-lymphotropic viruses denoted human T-lymphotropic viruses 3 and 4 (HTLV-3 and HTLV4), that are believed to have resulted from cross-species transmission at some point in the past. It has been previously established that HTLV-1 causes adult T cell leukemia and other inflammatory diseases;...

Published: 7/25/2024 | Inventor(s): William Switzer, Walid Heneine, Thomas Folks

Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DCXXXX, DDXXXX, DXXXXX, OID-NCHHSTP-DHPSE, OID-NCHHSTP-DSTDP, primate, T-LYMPHOTROPIC, Viruses, VLXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, WJXXXX, WMXXXX, XCXXXX, XEXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Diagnostics, Application > Occupational Safety and Health