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Nucleic Acid Primers and Probes for Detecting Ebola Virus (species Zaire ebolavirus)

The 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa was the largest in history, causing more than 28,000 suspected, probable, and confirmed infections and more than 11,000 deaths across nine countries. CDC scientists designed nucleic acid primers and probes which can be used in a sensitive test for detecting all known strains of Ebola virus...

Published: 7/25/2024 | Inventor(s): Tara Sealy, Ute Stroeher, Stuart Nichol, Jonathan Towner

Keywords(s): 7, Acid, antibodies, ANTIGENS, assay, DETECTING, Detection, Ebola, Ebolavirus, ELISA, Enzyme, Identification, immunosorbent, LINKED, Listed LPM Kirby as of 4/15/2015, Mab, monoclonal, Mouse, NCEZID, NCEZID-DHCPP, Nucleic, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMERS, Probes, Species, Used, virus, Viruses, Zaire

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Mouse Monoclonal Antibody to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)

Oxidative stress resulting in the formation of biological radicals has been implicated in a number of human diseases, such as cancer as well as aging. There is, however, a paucity of reliable methods for in vivo or ex vivo detection of radical formation. Until now the only general technique that allowed for the detection of these highly reactive species...

Published: 7/25/2024 | Inventor(s): Marilyn (Estate of) Ehrenshaft, Ronald Mason

Keywords(s): 5, 5-dimethyl-1-pyrroline, AC5XXX, ACXXXX, ANTIBODY, AXXXXX, Detection, DMPO, ELISA, End-products, I cell disease, MBb, ML 2, ML 3 A, ML 4, monoclonal, Mouse, Mucolipidosis type 3 A, Mucolipidosis type 4, Nitrone, N-oxide, Protein, Radicals, RXXXXX, Sandwich, Specific, SPIN, STABLE, TRAP

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials