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Nucleic Acid Primers and Probes for Detecting Ebola Virus (species Zaire ebolavirus)

The 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa was the largest in history, causing more than 28,000 suspected, probable, and confirmed infections and more than 11,000 deaths across nine countries. CDC scientists designed nucleic acid primers and probes which can be used in a sensitive test for detecting all known strains of Ebola virus...

Published: 7/25/2024 | Inventor(s): Tara Sealy, Ute Stroeher, Stuart Nichol, Jonathan Towner

Keywords(s): 7, Acid, antibodies, ANTIGENS, assay, DETECTING, Detection, Ebola, Ebolavirus, ELISA, Enzyme, Identification, immunosorbent, LINKED, Listed LPM Kirby as of 4/15/2015, Mab, monoclonal, Mouse, NCEZID, NCEZID-DHCPP, Nucleic, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMERS, Probes, Species, Used, virus, Viruses, Zaire

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Human-derived Monoclonal Antibody for Treatment of Ebola Virus Infection

Ebola virus infection can lead to severe hemorrhagic fever, known as Ebola virus disease (EVD), which is often fatal. The Zaire species of Ebola virus (EBOV) was responsible for the largest Ebola outbreak in history, which occurred in 2014. Scientists at the NIAID Vaccine Research Center have developed a human monoclonal neutralizing antibody, mAb114...

Published: 7/25/2024 | Inventor(s): Antonio Lanzavecchia, Davide Corti, Barney Graham, Julie Ledgerwood, John Trefry, Daphne Stanley, Jean-Jacques Muyembe-Tamfun, Sabue Mulangu, Nancy Sullivan

Keywords(s): antibodies, Ebola, Ebolavirus, GLYCOPROTEIN, Listed LPM Thalhammer-Reyero as of 4/15/2015, monoclonal, Neutralize, Novel, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, That, THEREOF, USES, virus

Category(s): Collaboration Sought > Licensing