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Chimeric Antibodies Against Hepatitis B e-Antigen

The invention relates to recombinant chimeric rabbit/human monoclonal antibody fragments (Fabs) against hepatitis B Virus e-antigen (HBeAg), notably Fab me6. Viral hepatitis is the seventh leading cause of death worldwide. Hepatitis B core antigen (HBcAg) forms an icosahedral structure containing the viral genome. Both the HBcAg and the HBeAg of interest...

Published: 7/30/2024 | Inventor(s): Norman Watts, Alasdair Steven, Paul Wingfield

Keywords(s): Against, antibodies, APPLICATIONS, assay, B, CHARACTERIZATION, chimeric, Chimic, DB4XXX, E-antigen, FAB, Hepalitis, Hepatitis, Potential, Rabbit/human, Their, THERAPY, VLXXXX, WJXXXX, XAXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Immunology, Application > Therapeutics, TherapeuticArea > Infectious Disease, ResearchProducts > Antibodies

Mobile Instrumentation for the Detection and Sampling of Aerosol Particles

Hazardous airborne particles pose a risk for health and safety in a variety of environments and thus detection of these small particles is essential. Current particle magnification systems are bulky and require a lot of power for operation, making them unsuitable to easily detect and analyze small particles in mobile and personal settings. CDC/NIOSH...

Published: 7/25/2024 | Inventor(s): Gregory Deye, Pramod Kulkarni

Keywords(s): AEROSOL, APPLICATIONS, EXCHANGE, Growth, MEMBRANES, NIOSH-DART, PARTICLE, PERSONAL, Proton, Sampling, SYSTEMS, VBXXXX, VEXXXX, WAXXXX, WCXXXX, WGXXXX, WIXXXX, XDXXXX, XIXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics, Application > Vaccines, Application > Occupational Safety and Health

Use of Modified Peptide Nucleic Acids for Visualizing DNA

The compounds described in this technology may be useful in the development of nucleic acid detection kits for various pathogens. Technologies for genomic detection most commonly use DNA probes to hybridize to target sequences, and require the use of Polymerase Chain Reaction (PCR) to amplify target sequences. Replacing the DNA probe with peptide nucleic...

Published: 7/25/2024 | Inventor(s): Daniel Appella

Keywords(s): 2, Acid, Acids, Anthrax, APPLICATIONS, Cross-Coupled, Cyclopentan, Detection, Diamine-modified, Gamma-lysine, Modified, Nucleic, Patent Category - Chemistry, PATHOGENS, Peptide, Probes, SARS, Severe acute respiratory syndrome, Synthesis, Trans-1, YXXXXX

Category(s): Collaboration Sought > Collaboration