Search Results - zirconium-89

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89Zr-Oxine Complex for In Vivo PET Imaging of Labelled Cells and Associated Methods

Abstract: This technology from the NCI Molecular Imaging Program relates to a Zirconium-89 (89Zr)-oxine complex for cell labeling, tracking of labeled cells by whole-body positron emission tomography/computed tomography (PET/CT) imaging, and associated methods. A long half-life of 89Zr (78.4 hours), high sensitivity of PET, and absence of background...

Published: 4/8/2024 | Inventor(s): Noriko Sato, Haitao Wu, Gary Griffiths, Peter Choyke

Keywords(s): 89Zr, cell labeling, Oxine, zirconium-89

Category(s): Application > Research Materials, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology

Zirconium-89 PET Imaging Agent for Cancer

Abstract: Researchers at the NCI Radiation Oncology Branch and NIH CIT Center for Molecular Modeling developed a tetrahydroxamate chelation technology that provides a more-stable Zr-89 complex as an immuno-PET cancer imaging agent. In either the linear or the macrocyclic form, the tetrahydroxamate complexes exhibit greater stability as chelating agents...

Published: 5/23/2024 | Inventor(s): Francois Guerard, Yong-Sok Lee, Martin Brechbiel

Keywords(s): imaging agent, PET, zirconium-89

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Research Materials