Search Results - hellmut+merkle

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Denoising of Dynamic Magnetic Resonance Spectroscopic Imaging Using Low Rank Approximations in the Kinetic Domain

Abstract: Accurate measurement of low metabolite concentrations produced by medically important enzymes is commonly obscured by noise during magnetic resonance imaging (MRI). Measuring the turnover rate of low-level metabolites can directly quantify the activity of enzymes of interest, including possible drug targets in cancer and other diseases. Noise...

Published: 4/8/2024 | Inventor(s): Jeffery Brender, Kazutoshi Yamamoto, Jeeva Munasinghe, Shun Kishimoto, Hellmut Merkle, Murali Cherukuri, James Mitchell

Keywords(s): 13C imaging, Brender, Denoising, DNP, Dynamic Nuclear Polarization, Glucose Metabolism, Low Metabolite Concentration, Magnetic Resonance Imaging, Metabolic Enzymes, MRI, Software Plugin, SPECTROSCOPIC

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Software / Apps, TherapeuticArea > Oncology

Multilayered RF Coil System for Improving Transmit B1 Field Homogeneity in High-Field MRI

Available for licensing and commercial development is a multilayered radio-frequency (RF) coil system for improving the transmit B1 field homogeneity for magnetic resonance imaging (MRI) at high field strengths. The current invention aims at manipulating the inhomogeneous profile of the transmit B1 field, which causes MR images to become less uniform...

Published: 7/25/2024 | Inventor(s): Shumin Wang, Jozef (Jeff) Duyn, Hellmut Merkle, Alan Koretsky

Keywords(s): AA3AXX, AA3B1X, AA3BXX, AA3XXX, AAXXXX, AXXXXX, Circuitry, IMAGING, Magnetic Resonance, MRI, PASSIVE, Patent Category - Mech/Elect/Soft, RF coil

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing