Search Results - rheumatoid+arthritis

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Interleukin 24 (IL-24) to treat inflammatory diseases

Abstract: Proinflammatory T-helper 17 cells (Th17) play important roles in host immune defense against infection, but uncontrolled activation of these cells, known as the Th17 response, may cause autoimmune and autoinflammatory diseases (uveitis, multiple sclerosis, rheumatoid arthritis, and Crohn’s disease) through the effects of Th17 lineage...

Published: 4/8/2024 | Inventor(s): Rachel Caspi, Mary Mattapallil, Reiko Yamane, Wai Po Chong

Keywords(s): Caspi, Crohn’s disease, IL-24, inflammatory disease, interleukin 24, Multiple sclerosis, National Eye Institute, NEI, proinflammatory T-helper 17 cell, RHEUMATOID ARTHRITIS, Th17, uveitis

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology

Glucocorticoid-induced TNFR Family-Related Receptor Ligand (GITRL) Antibodies for Diagnosis and Treatment of Immune System Disorders

This technology provides novel antibodies and methods for diagnostics and treatment of disorders arising from dysregulation of the immune system using antibodies directed against glucocorticoid-induced tumor necrosis factor receptor family-related receptor ligand (GITRL). Also available are hybridomas producing anti-mouse GITRL monoclonal antibodies...

Published: 7/25/2024 | Inventor(s): Ethan Shevach

Keywords(s): antibodies, AUTOIMMUNE DISEASE, CD25, CD4, GITR, GITRL, IB3XXX, IBXXXX, IDXXXX, immune response, immune suppressor, IXXXXX, Multiple sclerosis, Patent Category - Biotechnology, RHEUMATOID ARTHRITIS, T cell, Treg

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, Application > Therapeutics