Search Results - roland+martin

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Myelin Basic Protein-specific T cell Clones TL3A6, TL5F6, and TL5G7

Autoreactive T cell clones such as TL3A6 and TL5F6 that recognize an autoantigen, which is potentially relevant for an autoimmune disease, for example, multiple sclerosis (MS), offer the potential to examine the disease pathogenesis and develop new treatments. Such treatments aim at disrupting or interfering with the specific interaction between autoreactive...

Published: 4/8/2024 | Inventor(s): Roland Martin, Henry McFarland

Keywords(s): ac5AXX, AC5XXX, ACXXXX, AXXXXX, BASIC, Cell, CLONES, Listed LPM Maddox as of 4/15/2015, MYELIN, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PROTEIN-SPECIFIC, T, TL3A6, TL5G7.

Category(s): Collaboration Sought > Licensing

Methods for the Selection of Subjects for Multiple Sclerosis Therapy

Multiple Sclerosis (MS) is a life-long chronic autoimmune disease diagnosed primarily in young adults who have a virtually normal life expectancy. Estimates place the annual costs of MS in the United States in excess of $2.5 billion. There are approximately 250,000 to 400,000 persons in the United States with MS, and approximately 2.5 million persons...

Published: 4/8/2024 | Inventor(s): Roland Martin

Keywords(s): IA3XXX, IAXXXX, IXXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Immunology, Application > Diagnostics, Application > Therapeutics

Method for the Treatment of Multiple Sclerosis

The invention relates to the discovery that humanized antibodies to the interleukin-2 receptor (IL-2R) such as (daclizumab) are effective in treating multiple sclerosis (MS). In particular, it has been discovered that patients who have failed to respond to therapy with interferon-beta show dramatic improvement when treated with daclizumab, with patients...

Published: 7/25/2024 | Inventor(s): Roland Martin

Keywords(s): IB3XXX, IBXXXX, IXXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials