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Methods of making and using dopamine receptor selective antagonists/partial agonists

Abstract: Dopamine is a major neurotransmitter in the central nervous system and among other functions is directly related to the rewarding effects of drugs of abuse. Dopamine signaling is mediated by D1, D2, D3, D4 and D5 receptors. The dopamine D3 receptor is a known target to treat a variety of neuropsychiatric disorders, including substance use...

Published: 4/8/2024 | Inventor(s): Amy Newman, Vivek Kumar, Anverbasha Shaik

Keywords(s): Bipolar Disorder, Cannabis, DEPENDENCE, dopamine D3 receptor, drug addiction, oxycodone, SCHIZOPHRENIA

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology, Application > Therapeutics