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Method of Manufacturing Papilloma Infiltrating Lymphocyte (PIL) Cell Therapy Products as a Treatment for Patients with Chronic Viral Infection(s)
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for development of papilloma-infiltrating lymphocytes (PIL) as treatment for patients with chronic human papillomavirus (HPV) 6 or 11 infections. Description of Technology: Recurrent Respiratory Papillomatosis (RRP) and anogenital condyloma are caused...
Published: 8/21/2025
|
Inventor(s):
Scott Norberg
,
Clint Allen
,
Zulmarie Franco
,
Ke Bai
Keywords(s):
Category(s):
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Immunology
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Method of Detecting Circulating Cell-Free HPV 6 and 11 DNA in Patients Afflicted With Diseases Caused by Chronic HPV 6 or 11 Infection and Use Thereof
Summary: The National Cancer Institute (NCI) and Frederick National Laboratory for Cancer Research (FNLCR) seek research co-development partners and/or licensees for commercial development of a novel liquid biopsy diagnostic for non-invasive detection of cell-free HPV 6 and 11 DNA for recurrent respiratory papillomatosis (RRP). Description of Technology: Recurrent...
Published: 8/21/2025
|
Inventor(s):
Scott Norberg
,
Clint Allen
,
Xiaolin Wu
Keywords(s):
Category(s):
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Oncology
,
TherapeuticArea > Pulmonology
,
Application > Diagnostics
,
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
T Cell Receptor Targeting HPV6 E2 and a Panel of Cos7 Cells Expressing Different HLA Class I Proteins for Use in Validation and Potency Studies
Summary: The National Cancer Institute (NCI) seeks licensees for this invention comprising (1) a novel T cell receptor (TCR) specific to the E2 protein of Human papillomavirus (HPV) type 6 in the context of the human leukocyte antigen, HLA-B55, and (2) a panel of Cos7 cells expressing different HLA proteins for validation of T cell responses in immunotherapies...
Published: 8/21/2025
|
Inventor(s):
Clint Allen
,
Scott Norberg
Keywords(s):
Category(s):
Application > Research Materials
,
TherapeuticArea > Immunology
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Biopsies
Summary: The National Cancer Institute (NCI) seeks co-development partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is an...
Published: 6/2/2025
|
Inventor(s):
Scott Norberg
,
Andrew Sinkoe
,
Xiaolin Wu
,
James Gulley
Keywords(s):
Category(s):
Application > Diagnostics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
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