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Clones Encoding Mammalian ADP-Ribosylarginine Hydrolases

ADP-ribosylation of arginine residues in proteins may be involved in cell adhesion and is crucial for the action of cholera toxin and E. coli heat-labile enterotoxin, agents involved in the pathogenesis of cholera and traveller's diarrhoea, respectively. ADP-ribosylation is reversed by ADP-ribosylarginine hydrolases, which cleave the ADP-ribose-arginine...

Published: 4/8/2024 | Inventor(s): Joel Moss, Sally Stanley, Maria Nightingale, James Murtagh, Lucia Monaco, Tatsuyuki Takada

Keywords(s): cholera, Cholera (Vibrio cholerae), DA3XXX, DAXXXX, DB3XXX, DBXXXX, DXXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Therapeutics