Search Results - therapeuticarea+%3e+cardiology

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Mass Spectrometry Derived Protein Biomarkers of Atherosclerotic Cardiovascular Disease Risk

This technology includes a combination of protein biomarkers and clinical risk factors to be used as an In Vitro Diagnostic Multivariate Index Assay (IVDMIA) that can improve the identification of individuals at high risk for atherosclerotic cardiovascular disease (ASCVD) and myocardial infarction (MI). Incorporation of novel protein biomarkers of ASCVD...

Published: 8/12/2024 | Inventor(s): Daniel Levy, Martin Larson, Aram Adourian, Pieter Muntendam

Keywords(s):

Category(s): Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology

Immunoassay-derived Protein Biomarkers of Atherosclerotic Cardiovascular Disease Risk

This technology includes a combination of 6 protein biomarkers and clinical risk factors to be used as an In Vitro Diagnostic Multivariate Index Assay (IVDMIA) that can improve the identification of individuals at high risk for atherosclerotic cardiovascular disease (ASCVD). Incorporation of novel protein biomarkers of ASCVD risk into risk assessment...

Published: 8/12/2024 | Inventor(s): Daniel Levy, Martin Larson, Ralph D'Agostino

Keywords(s):

Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Cardiology

PET Imaging of lntegrin Expression with Suitably Labeled RGD Peptides for Multiple Diagnostic Purposes

This technology includes a number of dimeric RGD peptides which been developed and labeled with various PET isotopes (1BF, 68Ga, and 64Cu) for imaging integrin expression in cancer, inflammation, rheumatoid arthritis, myocardial infarct, stroke and traumatic injury. A number of these peptides have been translated into clinic for diagnosis and therapy...

Published: 8/12/2024 | Inventor(s): Xiaoyuan (Shawn) Chen, Lixin Lang, Gang NIU

Keywords(s):

Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, TherapeuticArea > Neurology

An Automated System for Myocardial Perfusion Mapping and Machine Diagnosis to Detect Ischemic Heart Disease with First-pass Perfusion Cardiac Magnetic Resonance Imaging

This technology includes a fully automated computer aided diagnosis system to quantify myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) pixel maps from the first-pass contrast-enhanced cardiac magnetic resonance (CMR) perfusion images. This system performs automated image registration, motion compensation, segmentation, and modeling...

Published: 8/12/2024 | Inventor(s): Li-Yueh Hsu, Andrew Arai, Matthew Jacobs, Mitchel Benovoy

Keywords(s):

Category(s): Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology

3D Bioprinting of Cardiac Patch with Anisotropic and Perfusable Architecture for the Repair of Damaged Cardiac Muscle

This technology includes a novel cardiac patch which was 3D printed to repair damaged cardiac tissue. Based on biological and anatomical understanding of myocardial tissue, a novel 3D bioprinting technique was developed to directly fabricate the cellularized and vascularized cardiac patch with anisotropic fiber and perfusable vessel architecture. The...

Published: 8/12/2024 | Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang

Keywords(s):

Category(s): Application > Medical Devices, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology

Systems and Methods for Retrieving Implanted Magnets

This technology includes a strategy for retrieving a pair of implanted magnets from a patient’s body. This method includes maneuvering a guide catheter with a guide magnet on the distal end. Current methods are geared toward magnetic compression occurring in the digestive system, while this method can be used as a less invasive method for cardiac...

Published: 8/15/2024 | Inventor(s): Shaun Gittard, Kanishka Ratnayaka

Keywords(s):

Category(s): Application > Medical Devices, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology

Novel ApoC-11 Mimetic Peptides That Activate LPL for the Treatment of ApoC-11 Deficiency and Hypertriglyceridemia

This technology includes a new class of synthetic peptides that activate Lipoprotein Lipase (LPL), a key plasma enzyme that lowers triglycerides. Mutations in apoC-II is a genetic cause of severe hypertriglyceridemia, which can lead to cardiovascular disease and pancreatitis. The last helical domain (3rd helix) of apoC-ll activates LPL, and we discovered...

Published: 9/11/2024 | Inventor(s): Soumitra Ghosh, Chih-Hung (Larry) Lo, Alan Remaley, Denis Sviridov, Anna Wolska

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Cardiology

Device for Closure of Transvascular or Transcameral Access Ports

This technology includes part of transcatheter aortic valve replacement and to enable non-surgical thoracic aortic aneurysm endograft repair. The invention enables a completely new way to access the arterial circulation to allow introduction of large devices, such as transcatheter aortic valve replacement, percutaneous left ventricular assist devices,...

Published: 8/12/2024 | Inventor(s): Robert Lederman, Ozgur Kocaturk, Toby Rogers, Kanishka Ratnayaka, Nasser Rafiee

Keywords(s):

Category(s): Application > Medical Devices, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology

ApoE-ApoCII Chimeric Peptides for Treating Hypertriglyceridemia

This technology includes apoE-apoCII chimeric peptides that possess the ability to lower the triglyceride level both in vitro and in vivo. These peptides can be used for treating hypertriglyceridemia and alleviating other diseases and conditions associated with increased triglycerides.

Published: 9/11/2024 | Inventor(s): Soumitra Ghosh, Chih-Hung (Larry) Lo, Alan Remaley, Denis Sviridov, Anna Wolska, Madhav (Matt) Devalaraja

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, TherapeuticArea > Cardiology

Methods and Systems for Automatically Determining Magnetic Field Inversion Time of a Tissue Species

This technology includes a computer-implemented method for determining magnetic field inversion time of a tissue species using a T1-mapping image, information about the region of interest, and a tissue classification algorithm. This method includes T1-mapping image comprising a plurality of T1 values within an expected range of T1 values for the tissue...

Published: 8/12/2024 | Inventor(s): Bruce Spottiswoode, Xlaoguang Lu, Xiaoming Bi, Christopher Glielmi, Andreas Greiser, Hui Xue, Peter Kellman

Keywords(s):

Category(s): Application > Diagnostics, Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology

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