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Mice, Organs, and Mouse Alleles Carrying Germline and Conditional Deletions of the Zbtb7b Gene

Summary: The NCI seeks parties interested in licensing this mouse model, including the mice, organs, tissues, and other derivatives from mice carrying deletions of the Zbtb7b gene. Description: The Zbtb7b gene encodes the zinc finger transcription factor ThPOK (also known as cKrox) that promotes CD4 lineage differentiation in immature T cells. CD4+...

Published: 4/23/2026 | Updated: 8/2/2023 | Inventor(s):

Keywords(s): Autoimmunity, Bosselut, CANCER, CD4, cKrox, Helper T Cell, Infection, LYMPHOCYTE, Memory T Cell, Oncology, ThPOK, transgenic mice, Zbtb7b, Zinc Finger Transcription Factor

Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Research Materials, TherapeuticArea > Immunology