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Novel Anti-HIV Compounds Using Peptides or Peptide Mimetics
Abstract: The subject invention describes a new class of compounds (such as peptides or mimetics) that target viral RNAs and inhibit the viral life cycle by blocking the viral recognition process. More specifically, these compounds are the first against an RNA Target - currently there are no clinical drugs against RNA targets in the treatment of any...
Published: 4/8/2024
|
Inventor(s):
Yun-Xing Wang
,
Liu Yu
,
Ping Yu
,
Ina O'Carroll
Keywords(s):
Anti-Viral
,
HIV
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
Method and Device for Selectively Labeling RNA
Abstract: Current methods of labeling and synthesizing RNA do not allow for multiple labels or long RNA segments to be synthesized for large RNA on a milligram scale. Investigators at the NCI Structure Biophysics Lab and UT Health Science Center have developed a method to selectively label RNA at specific residues and/or segments using a hybrid solid-liquid...
Published: 12/10/2024
|
Inventor(s):
Yun-Xing Wang
,
Liu Yu
,
Rui Sousa
Keywords(s):
crystallography
,
Fluorophore labeling
,
FRET
,
Isotope labeling
,
Labeling sensor
,
NMR Spectroscopy
Category(s):
Application > Diagnostics
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
Real-Time PCR Assay for Specific Detection of Haemophilus influenzae Serotypes A and B
Haemophilus influenzae is responsible for life-threatening respiratory infections including meningitis. This assay allows for the qualitative detection of the bacterial meningitis pathogen H. influenzae serotype A (Hia) and serotype B (Hib) in fluid samples, without detecting any of the other serotypes of H. influenzae. This invention is capable of...
Published: 10/28/2024
|
Inventor(s):
Xin Wang
,
Cynthia Hatcher
,
Raydel Anderson
,
Mary Theodore
,
Leonard Mayer
,
Jennifer Thomas
Keywords(s):
CDC Docket Import
,
CDC Docket Import CDC Prosecuting
,
DA3XXX
,
DAXXXX
,
Detection
,
DXXXXX
,
HAEMOPHILUS
,
INFLUENZAE
,
OID-NCIRD-DBD
,
SELECTIVE
Category(s):
Collaboration Sought > Licensing
,
TherapeuticArea > Infectious Disease
,
Application > Diagnostics
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