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Therapeutic Immunotoxins with Increased Half-Life and Anti-Tumor Activity

Abstract: Recombinant Immunotoxins (RITs) are chimeric molecules composed of an antigen binding domain and toxin. The antigen binding domain component targets the cancer cell and delivers the toxin component to the cell. However, the efficacy of RITs is limited by their short half-life once they are in the patient. To address this problem, investigators...

Published: 5/21/2024 | Inventor(s): Ira Pastan, Zeliang Zheng

Keywords(s): Immunotherapy, MESOTHELIN, Mesothelioma, Pastan, Recombinant Immunotoxins, RITs

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics