HOME
SEARCH
RSS FEED
SUBSCRIBE
Creation and Use of Kinetin Derivatives for Treating RNA Missplicing Diseases Such as Familial Dysautonomia
Case ID:
TAB-3580
Web Published:
12/6/2022
Description:
This technology includes the creation and use of compounds, including kinetin derivatives, that improve mRNA splicing in a cell for the treatment of disorders associated with misspliced mRNA, including familial dysautonomia (FD). FD, the best-known and most common member of a group of congenital sensory and autonomic neuropathies, affects neuronal development and is associated with progressive neuronal degeneration. This disease is caused by mutations in the splicing of intron 20 of the IKMKAP gene that results in a unique pattern of tissue-specific exon skipping.
Patent Information:
Title
App Type
Country
Serial No.
Patent No.
File Date
Issued Date
Expire Date
Patent Status
Direct Link:
https://nih.technologypublisher.com/tech/Creation_and_Use_of_Kinetin_Derivati ves_for_Treating_RNA_Missplicing_Diseases_Such_as_Familial_Dysautonomia
Category(s):
Therapeutics
Neurology
Bookmark this page
Download as PDF
For Information, Contact:
Suryanarayana Vepa
Technology Licensing Specialist
NIH Technology Transfer
301-827-7181
sury.vepa@nih.gov
Inventors:
Juan Marugan
Susan Slaugenhuapt
Keywords:
Derivatives
Kinetin
VEXXXX
WKXXXX
XEXXXX
Home
|
Search
|
RSS
|
Subscribe
© 2024. All Rights Reserved. Powered by
Inteum