Intranasal or Inhaled Delivery of a Custom IgA Antibody for Protection Against COVID-19

Description:

This technology includes an IgA antibody, specifically designed to target the receptor binding domain of SARS-CoV-2, the virus causing COVID-19. Administered intranasally, this antibody has potential neutralizing activity, aiming to prevent COVID-19. IgA, an antibody class present in mucosal areas, plays a crucial role in immune defense at the initial site of viral infection. The primary application of this technology is envisioned as a therapeutic nasal spray, intended to prevent SARS-CoV-2 infection, particularly in high-risk populations. This approach represents a targeted method to bolster defenses against COVID-19 at its point of entry in the human body.

Patent Information:
For Information, Contact:
Lunet Luna
Technology Transfer Manager
NIH Technology Transfer
301.443.7786
lunet.luna@nih.gov
Inventors:
Kaitlyn Sadtler
Mathew Memoli
Keywords:
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