Regulator of G Protein Signaling (RGS13) Knock-Out Mouse

Description:
RGS13, an intracellular protein in mast cells, was shown to suppress IgE-mediated anaphylactic response in mice. The RGS13-/- mouse may be used to screen compounds that inhibit mast cell degranulation.
Patent Information:
For Information, Contact:
Daniel Lee
TTPS/Technology Transfer Manager
NIH Technology Transfer
301-761-6327
daniel.lee5@nih.gov
Inventors:
Zhi Hui (Sherry) Xie
Kirk Druey
Keywords:
Anaphylactic
Cells
IGE-MEDIATED
Intracellutar
Knockout
Listed LPM Maddox as of 4/15/2015
MAST
Mice
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
Protein
RESPONSE
RGS13
RM
RXXXXX
Suppresses
That
WIXXXX
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