Software for Modeling Delivery and Penetration of Antibody Conjugates

Description:

Abstract:

The National Cancer Institute (NCI) seeks parties to license software for modeling the targeted delivery of anti-cancer agents in solid tumors.

The software models the permeability and concentration of intravenously administered antibody anti-cancer agent conjugates in solid tumors.  The models can be used to determine optimal dosing regimen of a therapeutic in a particular cancer type.  Thirty factors that affect delivery rates and efficiencies are analyzed as variables in generating the models.

Competitive Advantages:

  • Accurate permeability modeling of anti-cancer therapeutics.

Commercial Applications:

  • Drug design
  • Combination therapy
  • Personalized medicine
Patent Information:
For Information, Contact:
David Lambertson
Senior Technology Transfer Manager
NIH Technology Transfer
david.lambertson@nih.gov
Inventors:
Byungkook Lee
Youngshang Pak
Ira Pastan
Keywords:
Anti-Cancer Modeling
Dosing
Drug Design
Tumor Delivery
Tumor Penetration
© 2024. All Rights Reserved. Powered by Inteum