Amino Acid Substitutions Mutants of Anthrax Protective Antigen, Lethal Factor, and Edema Factor

Description: Anthrax toxin proteins available for licensing. Bacillus anthracis hosts containing plasmids expressing the following proteins are available. (Host strains are generally BH480, or sometimes BH460. Modest amounts of purified proteins (10-50 mg) could also be provided):

1. PA. Protective antigen, wild type
2. PA-3M (PA D683A, L685E, Y688K)
3. PA-3M Cys
4. PA-U7
5. PA F427A
6. PA K563C
7. PA L687A
8. PA-U7 K562C
9. PA D512K
10. PA GN
11. PA-3M SoSi-H6
12. FP59-AGG
13. EF-A K313R
14. LFn-linker-Cys
15. LF E687A
16. LFnBLA
17. LFnFLA

Category(s):

Licensing

Infectious Disease

Research Materials