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Myelin Basic Protein-specific T cell Clones TL3A6, TL5F6, and TL5G7
Case ID:
TAB-1130
Web Published:
12/6/2022
Description:
Autoreactive T cell clones such as TL3A6 and TL5F6 that recognize an autoantigen, which is potentially relevant for an autoimmune disease, for example, multiple sclerosis (MS), offer the potential to examine the disease pathogenesis and develop new treatments. Such treatments aim at disrupting or interfering with the specific interaction between autoreactive T cells, antigen presenting cells and antigenic peptide. Current treatments have immunomodulatory effects and side effects. These T cell lines will be useful for developing novel treatment approaches for multiple sclerosis. The T cell lines can be used to test treatments that block or interfere with surface receptors of these cells.
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Direct Link:
https://nih.technologypublisher.com/tech?title=Myelin_Basic_Protein-specific_ T_cell_Clones_TL3A6%2c_TL5F6%2c_and_TL5G7
Category(s):
Licensing
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For Information, Contact:
Inteum Admin
NIH Technology Transfer
Inventors:
Roland Martin
Henry McFarland
Keywords:
ac5AXX
AC5XXX
ACXXXX
AXXXXX
BASIC
Cell
CLONES
Listed LPM Maddox as of 4/15/2015
MYELIN
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
PROTEIN-SPECIFIC
T
TL3A6
TL5G7.
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