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Rabbit Polyclonal Antiserum to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)
Case ID:
TAB-2958
Web Published:
12/6/2022
Description:
Biological radicals resulted from oxidative stress has been implicated in human diseases, such as cancer and aging. There is, however, a paucity of reliable methods for
in vivo
or
ex vivo
detection of either radical formation, the end-products of radical formation or susceptibility for radical formation. The Rabbit polyclonal anti-DMPO can be used to detect the stable nitrone end-product of protein and DNA radicals in ELISA assays, blot analyses and confocal microscopy. This rabbit polyclonal anti-DMPO antiserum will replace a previously licensed one which is no longer available (E-186-2003). The availability of anti-DMPO from three different sources will greatly expand the ability of researchers to use anti-DMPO in conjunction with other antibodies.
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Direct Link:
https://nih.technologypublisher.com/tech?title=Rabbit_Polyclonal_Antiserum_to _the_Nitrone_Spin_Trap_5%2c5-dimethyl-1-pyrroline_N-oxide_(DMPO)
Category(s):
Licensing
Research Materials
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For Information, Contact:
Vidita Choudhry
Technology Development Specialist
NIH Technology Transfer
301-594-4095
vidita.choudhry@nih.gov
Inventors:
Marilyn (Estate of) Ehrenshaft
Ronald Mason
Keywords:
5
5-dimethyl-1-pyrroline
Antiserum
DMPO
Listed LPM Vepa as of 4/15/2015
Nitrone
N-oxide
polyclonal
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
rabbit
SPIN
TRAP
WIXXXX
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