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Detecting Levels of Chymotrypsin and Amylase using Rabbit Polyclonal Antibodies Generated from Purified Human Enzymes

The invention relates to rabbit antisera raised against purified human chymotrypsin and amylase. Both chymotrypsin and amylase are produced by the pancreas and play important roles in digestion. Abnormal levels of chymotrypsin and amylase have been known to occur with multiple pancreas-related disorders, including pancreatitis. Measuring levels of these...

Published: 7/25/2024 | Inventor(s): David Jacobowitz

Keywords(s): Amylase, antibodies, Chymotrypsin, Human, Listed LPM Maddox as of 4/15/2015, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, VPXXXX, WBXXXX, WIXXXX, XAXXXX

Category(s): TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Antibodies, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental

RL-5 – Rabbit T Cell Line Derived From a Herpesvirus Ateles-induced Rabbit Tumor From the Inbred Rabbit Line B/J

Details for this material are provided in the NIH AIDS Reagent Program Catalog (Catalog# 341): https://www.aidsreagent.org/reagentdetail.cfm?t=cell_lines&id=152.

Published: 7/25/2024 | Inventor(s): Bishop Hague

Keywords(s): Ateles-induced, B/J., Cell, DERIVED, HERPESVIRUS, Inbred, Line, Listed LPM Ano as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, RL-5-, RM, T, tumor, VLXXXX, WIXXXX

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, TherapeuticArea > Infectious Disease, Application > Research Materials

Rabbit Antibody to Mouse Sphingosine kinase 2 (SphK2)

Two isoforms of sphingosine kinase, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2), convert sphingosine to sphingosine 1-phosphate (S1P) in mammalian cells. While the importance of SphK1 has been known for some time, information about SphK2 is still being revealed. Therefore, researchers at NIH have developed an antibody against mouse...

Published: 7/25/2024 | Inventor(s): Richard Proia

Keywords(s): 2, ANTIBODY, IDXXXX, IXXXXX, Kinase, Mouse, rabbit, Sphingosine

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics

Rabbit Antibody to Mouse Sphingosine-1-phosphate (S1P) lyase

The cleavage of sphingoid base phosphates by sphingosine-1-phosphate (S1P) lyase to produce phosphoethanolamine and a fatty aldehyde is the final degradative step in the sphingolipid metabolic pathway. Researchers at NIH injected rabbits with the C-terminal peptide of the mouse S1P lyase — 551-TTDPVTQGNQMNGSPKPR-568 — to develop an antibody that can...

Published: 7/25/2024 | Inventor(s): Richard Proia

Keywords(s): ANTIBODY, IDXXXX, IXXXXX, Lyase, Mouse, rabbit, S1P

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Research Materials, Application > Diagnostics

Rabbit Polyclonal Antibody to Detect a Pro-peptide Fragment of NSAID-activated Gene (NAG-1)/GDF15, a Protein Associated with Cancer

Chronic inflammation is clearly associated with an increase in the risk of cancer. Non-steroidal anti-inflammatory drugs (NSAIDs) are well documented as agents that inhibit tumor growth and with long-term use can prevent tumor development. NSAID-activated gene (NAG-1), a unique member of the TGF-beta superfamily, is highly induced by NSAIDs and numerous...

Published: 7/25/2024 | Inventor(s): Thomas Eling

Keywords(s): ANTIBODY, CC3AXX, CC3XXX, CCXXXX, CXXXXX, Detection, NAG-1/Gdf15, polyclonal, Pro-peptide, rabbit

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, TherapeuticArea > Oncology

Polyclonal Antibodies to the Kidney Protein Urea Transporter 1 (UTA1)

Antibodies to UTA1, useful for immunoblotting and immunocytochemistry, are available to resell for research purposes. Urea Transporter 1 (UTA1) is activated by vasopressin and is responsible for urea transport across the apical membrane into the intracellular space within the renal inner medullary collecting duct. The inventor has developed rabbit...

Published: 7/25/2024 | Inventor(s): Mark Knepper

Keywords(s): ANTIBODY, Polycionai, rabbit, RXXXXX, UT-A1-LL194

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials

Rabbit Polyclonal Antiserum to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)

Biological radicals resulted from oxidative stress has been implicated in human diseases, such as cancer and aging. There is, however, a paucity of reliable methods for in vivo or ex vivo detection of either radical formation, the end-products of radical formation or susceptibility for radical formation. The Rabbit polyclonal anti-DMPO can be used...

Published: 7/25/2024 | Inventor(s): Marilyn (Estate of) Ehrenshaft, Ronald Mason

Keywords(s): 5, 5-dimethyl-1-pyrroline, Antiserum, DMPO, Listed LPM Vepa as of 4/15/2015, Nitrone, N-oxide, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, SPIN, TRAP, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Antibodies that Selectively Detect the Human Nestin Protein

Nestin is an intermediate filament protein first described in early embryonic neuroepithelial stem cells. Although not found in most cells of the mature CNS, nestin is the predominant marker used to detect the small population of undifferentiated cells. The presence of nestin identifies stem, progenitor and some tumor cells in the CNS, and also labels...

Published: 7/25/2024 | Inventor(s): Conrad Messam, Eugene Major, Jean Hou

Keywords(s): Antisera, Cross, Human, Listed LPM Maddox as of 4/15/2015, Nestin, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, R1XXXX, rabbit, Reactive, Rodent, RXXXXX, Specific, X

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Rabbit Antisera to Various Matrix, Matricellular, and Other Secreted Proteins

The extracellular matrix (ECM) is composed of a group of proteins that regulate many cellular functions, such as cell shape, adhesion, migration, proliferation, and differentiation. Deregulation of ECM protein production or function contributes to many pathological conditions, including asthma, chronic obstructive pulmonary disease, arthrosclerosis,...

Published: 7/25/2024 | Inventor(s): Larry Fisher

Keywords(s): ANIMAL, Antisera, Human, Listed LPM Maddox as of 4/15/2015, Matricellular, MATRIX, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, proteins, rabbit, RXXXXX, SECRETED, VARIOUS, VAXXXX, VCXXXX, VDXXXX, VGXXXX, VIXXXX, WIXXXX, XAXXXX, XCXXXX, YAXXXX

Category(s): TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, TherapeuticArea > Oncology, ResearchProducts > Antibodies, Application > Research Materials, TherapeuticArea > Immunology, TherapeuticArea > Geriatrics, Application > Diagnostics