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Real-time PCR Assays for Selective Detection and Differentiation of B. pertussis, B. parapertussis and B. homesii
Case ID:
TAB-2640
Web Published:
12/6/2022
Description:
CDC researchers developed a real-time PCR assay targeting insertion sequence (IS481) and pertussis toxin subunit 1 (ptxS1) of
Bordetella pertussis
. This real-time nucleic acid assay offers rapid, sensitive, and quantitative results. The employed primers have been validated through extensive diagnostic testing of 41
Bordetella
and 64 non-
Bordetella
clinical isolates. This technology can be used to diagnose and distinguish
B. pertussis
,
B. parapertussis
and
B. homesii
, the three most common
Bordetella
human upper respiratory pathogens. A standalone assay or multi-faceted kit may be used.
Patent Information:
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Direct Link:
https://nih.technologypublisher.com/tech?title=Real-time_PCR_Assays_for_Selec tive_Detection_and_Differentiation_of_B._pertussis%2c_B._parapertussis_and_B._homesii
Category(s):
Licensing
Infectious Disease
Diagnostics
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For Information, Contact:
Jonathan Motley
Fellow
NIH Technology Transfer
jonathan.motley@nih.gov
Inventors:
Kansas Sparks
Maria-Lucia Tondella
Kathleen Tatti
Keywords:
BORDETELLA
CDC Docket Import
CDC Docket Import CDC Prosecuting
DA3XXX
DAXXXX
Detection
DXXXXX
SELECTIVE
Species
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