Search Results - 7-methoxy-3-4-phenylbutyl-2

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Novel NMDA ligands that are specific and selective to the NR2B subunits based on the derivatives of 7-methoxy-3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ol

This invention includes the design and synthesis of ligands that bind selectively and specifically to the NR2B subunit of the NMDA receptor. The NMDA receptor is thought to play a role in the pathophysiology of psychiatric disorders, including depression, stroke, drug addiction, and neuropathic pain. Existing ligands to the NMDA receptor are widely...

Published: 7/25/2024 | Inventor(s): Victor Pike, Lisheng Cai

Keywords(s): 3, 4, 5-tetrahydro-1H-benzo[d]azepin-1-ol, 7-methoxy-3-4-phenylbutyl-2, Based, Derivatives, LIGANDS, NR2B, VNXXXX, WIXXXX

Category(s): Application > Research Materials, TherapeuticArea > Psychiatry/Mental Health