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Neutralizing Monoclonal Antibodies Against West Nile Virus
West Nile virus (WNV) is a mosquito-borne flavivirus that can cause fever and, in some cases, severe neurologic disease. There is no approved human vaccine or specific antiviral treatment for WNV. Researchers at NIAID's Vaccine Research Center (VRC), working with collaborators at Sheba Medical Center under the PREMISE program, identified...
Published: 4/24/2026
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Updated: 4/24/2026
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Inventor(s):
Daniel Douek
,
Chaim Schramm
,
Ananda Chowdhury
,
Parker Dabbs
,
Lu Wang
,
Leonid Serebryannyy
,
Theodore Pierson
,
Kimberly Dowd
,
Laura Vanblargan
,
Katherine Burgomaster
,
David Gordon
,
Yuxiang Wang
,
Yaniv Lustig
,
Yael Ottolenghi
,
Dror Harats
,
Sarah Smith (Kerscher)
Keywords(s):
Category(s):
Application
,
ResearchProducts > Virus/Bacteria
,
ResearchProducts
,
ResearchProducts > Antibodies
,
TherapeuticArea
,
Application > Diagnostics
Neutralizing Antibodies Against West Nile Virus
West Nile virus (WNV) is a mosquito-borne virus that can cause severe disease affecting the brain and nervous system, especially in older adults and people with weakened immune systems. There is no approved human vaccine or specific antiviral treatment for WNV. Researchers at NIAID’s Vaccine Research Center (VRC), together with collaborators...
Published: 4/23/2026
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Updated: 4/22/2026
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Inventor(s):
Theodore Pierson
,
Kimberly Dowd
,
Daniel Douek
,
Dror Harats
,
Yael Ottolenghi
,
Gili Regev-Yochay
,
Yaniv Lustig
Keywords(s):
Category(s):
TherapeuticArea
,
Application > Vaccines
,
Application
,
Application > Diagnostics
,
ResearchProducts
,
ResearchProducts > Virus/Bacteria
DNA Methylation-Based Cancer Diagnostics for Accurate Tumor Classification
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a collection of T-cell receptors (TCRs) that specifically target the mutated KRAS antigen. This technology encompasses a DNA methylation–based diagnostic platform designed to improve the accuracy and consistency of cancer classification,...
Published: 4/23/2026
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Updated: 4/10/2026
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Inventor(s):
Kenneth Aldape
,
Ziedulla Abdullaev
,
Rustamzhon Turakulov
,
Stefania Pittaluga
,
Mark Raffeld
,
Elaine Jaffe
,
Omkar Singh
,
Antonios Papanicolau-Sengos
Keywords(s):
Category(s):
Application > Diagnostics
,
TherapeuticArea > Oncology
,
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio
CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides additional room at the base of the well to enable optimal cartridge immersion and analyte diffusion. The microplate is readily adaptable into existing automated analytical...
Published: 4/10/2026
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Updated: 4/8/2026
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Inventor(s):
Ashley Ribera
,
Hui Zhou
,
Hubert Vesper
Keywords(s):
Category(s):
Application > Diagnostics
,
Application > Research Materials
,
Collaboration Sought
,
TherapeuticArea
,
TherapeuticArea > Endocrinology
,
TherapeuticArea > Geriatrics
,
TherapeuticArea > Hematology
,
TherapeuticArea > Obstetrics/Neo-Natal
,
TherapeuticArea > Reproductive Health
,
TherapeuticArea > Urology
Real-time AI System for Echocardiography Analysis and Quantification
Summary: We are seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. Description of Technology: Scientists have developed an artificial intelligence (AI) system to automatically extract predictive biomarkers from echocardiography. This AI system...
Published: 2/18/2026
|
Updated: 2/18/2026
|
Inventor(s):
Ghada Alzamzmi
,
Sameer Antani
,
Li-Yueh Hsu
,
Vandana Sachdev
,
Sivarama Krishnan Rajaraman
Keywords(s):
Category(s):
Application > Diagnostics
,
TherapeuticArea > Cardiology
,
Collaboration Sought > Collaboration
,
Application > Software / Apps
Humanized Monoclonal Antibodies Specific Against Human Soluble Tissue Factor (hsTF) as Diagnosis, Prevention and Therapeutic Agents for Thrombosis
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a novel humanized monoclonal antibody (58B3) that selectively targets a newly identified soluble Tissue Factor (sTF) to diagnose, prevent and treat pathological thrombosis associated with inflammation, viral/bacterial infection, sepsis and cancer...
Published: 2/11/2026
|
Updated: 9/29/2025
|
Inventor(s):
Zheng-gang Liu
,
Swati Choksi
,
PeiXing Wan
Keywords(s):
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Immunology
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Oncology
,
Application > Diagnostics
,
Application > Therapeutics
Innovative Antibody Conjugation Technology for Therapeutic and Diagnostic Applications
This pioneering technology introduces a novel method for conjugating antibodies, designed to dramatically enhance their therapeutic and diagnostic performance. By improving both binding efficiency and target specificity, this approach overcomes critical limitations of existing antibody-based therapies and imaging tools. The result is a versatile platform...
Published: 4/14/2026
|
Updated: 9/22/2025
|
Inventor(s):
Parinaz Fathi
,
Frank Borris
,
Kaitlyn Sadtler
Keywords(s):
Category(s):
Application
,
Application > Therapeutics
,
Application > Diagnostics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Infectious Disease
Rapid Spectral Unmixing Using Spectrally Interpolated Background Reduction (SIBR) for Fluorescence Imaging
This breakthrough technology introduces Spectrally Interpolated Background Reduction (SIBR), a novel process that enables the rapid and efficient calculation of fluorescence signals from individual probes in complex, multi-labeled samples. Unlike traditional methods that require extensive computational power, SIBR provides real-time unmixing of signals...
Published: 12/19/2025
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Updated: 9/22/2025
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Inventor(s):
Harshad Vishwasrao
Keywords(s):
Category(s):
Application > Medical Devices
,
Application > Research Materials
,
Application > Diagnostics
Innovative Antibody Conjugates for Targeted Therapy
This advanced technology introduces innovative antibody conjugates that redefine the possibilities of targeted therapy. By coupling therapeutic agents to engineered antibodies with highly specific binding sites, these conjugates deliver treatments directly to diseased cells while sparing healthy tissues. The result is a powerful increase in treatment...
Published: 1/2/2026
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Updated: 9/22/2025
|
Inventor(s):
Nicole Morgan
,
Paniz Rezvan Sangsari
,
Parinaz Fathi
,
Kaitlyn Sadtler
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Diagnostics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
Innovative Antibody Conjugates for Targeted Therapeutics
This cutting-edge technology leverages innovative conjugated antibodies to transform the way diseases are treated. By engineering antibodies to deliver therapeutic agents directly to specific cells, this approach offers a powerful combination of precision, potency, and safety. Unlike traditional therapies that often impact healthy tissues and cause...
Published: 1/2/2026
|
Updated: 9/22/2025
|
Inventor(s):
Kaitlyn Sadtler
,
Devon Hartigan
,
Katharina Maisel
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Diagnostics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
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