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Monoclonal Antibody for Specific Detection of the Transcription Factor Eos (Ikzf4) in Regulatory T Cells

Regulatory T cells (Tregs) are immune cells that keep the immune system balanced and prevent autoimmunity. Tregs depend on a protein called Eos (Ikzf4) that helps turn genes on and off for their development and function, but until now, antibodies used to detect and study Eos were unreliable. Researchers at the National Institute of Allergy and Infectious...

Published: 6/3/2026 | Updated: 6/3/2026 | Inventor(s): Ethan Shevach, Angela DeVico, Patricia Korty

Keywords(s):

Category(s): ResearchProducts, Application, Application > Diagnostics, Application > Therapeutics

Neutralizing Monoclonal Antibodies Against West Nile Virus

West Nile virus (WNV) is a mosquito-borne flavivirus that can cause fever and, in some cases, severe neurologic disease. There is no approved human vaccine or specific antiviral treatment for WNV. Researchers at NIAID's Vaccine Research Center (VRC), working with collaborators at Sheba Medical Center under the PREMISE program, identified...

Published: 4/24/2026 | Updated: 4/24/2026 | Inventor(s): Daniel Douek, Chaim Schramm, Ananda Chowdhury, Parker Dabbs, Lu Wang, Leonid Serebryannyy, Theodore Pierson, Kimberly Dowd, Laura Vanblargan, Katherine Burgomaster, David Gordon, Yuxiang Wang, Yaniv Lustig, Yael Ottolenghi, Dror Harats, Sarah Smith (Kerscher)

Keywords(s):

Category(s): Application, ResearchProducts > Virus/Bacteria, ResearchProducts, ResearchProducts > Antibodies, TherapeuticArea, Application > Diagnostics

Neutralizing Antibodies Against West Nile Virus

West Nile virus (WNV) is a mosquito-borne virus that can cause severe disease affecting the brain and nervous system, especially in older adults and people with weakened immune systems. There is no approved human vaccine or specific antiviral treatment for WNV. Researchers at NIAID’s Vaccine Research Center (VRC), together with collaborators...

Published: 4/23/2026 | Updated: 4/22/2026 | Inventor(s): Theodore Pierson, Kimberly Dowd, Daniel Douek, Dror Harats, Yael Ottolenghi, Gili Regev-Yochay, Yaniv Lustig

Keywords(s):

Category(s): TherapeuticArea, Application > Vaccines, Application, Application > Diagnostics, ResearchProducts, ResearchProducts > Virus/Bacteria

DNA Methylation-Based Cancer Diagnostics for Accurate Tumor Classification

Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a collection of T-cell receptors (TCRs) that specifically target the mutated KRAS antigen. This technology encompasses a DNA methylation–based diagnostic platform designed to improve the accuracy and consistency of cancer classification,...

Published: 4/23/2026 | Updated: 4/10/2026 | Inventor(s): Kenneth Aldape, Ziedulla Abdullaev, Rustamzhon Turakulov, Stefania Pittaluga, Mark Raffeld, Elaine Jaffe, Omkar Singh, Antonios Papanicolau-Sengos

Keywords(s):

Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Real-time AI System for Echocardiography Analysis and Quantification

Summary: We are seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize this technology. Description of Technology: Scientists have developed an artificial intelligence (AI) system to automatically extract predictive biomarkers from echocardiography. This AI system...

Published: 2/18/2026 | Updated: 2/18/2026 | Inventor(s): Ghada Alzamzmi, Sameer Antani, Li-Yueh Hsu, Vandana Sachdev, Sivarama Krishnan Rajaraman

Keywords(s):

Category(s): Application > Diagnostics, TherapeuticArea > Cardiology, Collaboration Sought > Collaboration, Application > Software / Apps

Soluble Tissue Factor, a Novel Target, and Antibodies, for Diagnosis, Prevention and Treatment of Thrombosis and Related Conditions

Summary: Scientists at the National Cancer Institute (NCI) have discovered a novel therapeutic, diagnostic and prognostic target for thrombosis: Soluble Tissue Factor (sTF). NCI has generated first-in-class antibodies and platform selectively neutralizing pathological coagulation while preserving normal hemostasis. This platform technology can be used...

Published: 5/12/2026 | Updated: 9/29/2025 | Inventor(s): Zheng-gang Liu, Swati Choksi, PeiXing Wan, Yeon-Ji Park

Keywords(s):

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, Application > Diagnostics, Application > Therapeutics

Innovative Antibody Conjugation Technology for Therapeutic and Diagnostic Applications

This pioneering technology introduces a novel method for conjugating antibodies, designed to dramatically enhance their therapeutic and diagnostic performance. By improving both binding efficiency and target specificity, this approach overcomes critical limitations of existing antibody-based therapies and imaging tools. The result is a versatile platform...

Published: 4/14/2026 | Updated: 9/22/2025 | Inventor(s): Parinaz Fathi, Frank Borris, Kaitlyn Sadtler

Keywords(s):

Category(s): Application, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease

Rapid Spectral Unmixing Using Spectrally Interpolated Background Reduction (SIBR) for Fluorescence Imaging

This breakthrough technology introduces Spectrally Interpolated Background Reduction (SIBR), a novel process that enables the rapid and efficient calculation of fluorescence signals from individual probes in complex, multi-labeled samples. Unlike traditional methods that require extensive computational power, SIBR provides real-time unmixing of signals...

Published: 12/19/2025 | Updated: 9/22/2025 | Inventor(s): Harshad Vishwasrao

Keywords(s):

Category(s): Application > Medical Devices, Application > Research Materials, Application > Diagnostics

Innovative Antibody Conjugates for Targeted Therapy

This advanced technology introduces innovative antibody conjugates that redefine the possibilities of targeted therapy. By coupling therapeutic agents to engineered antibodies with highly specific binding sites, these conjugates deliver treatments directly to diseased cells while sparing healthy tissues. The result is a powerful increase in treatment...

Published: 1/2/2026 | Updated: 9/22/2025 | Inventor(s): Nicole Morgan, Paniz Rezvan Sangsari, Parinaz Fathi, Kaitlyn Sadtler

Keywords(s):

Category(s): Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology, TherapeuticArea > Immunology

Innovative Antibody Conjugates for Targeted Therapeutics

This cutting-edge technology leverages innovative conjugated antibodies to transform the way diseases are treated. By engineering antibodies to deliver therapeutic agents directly to specific cells, this approach offers a powerful combination of precision, potency, and safety. Unlike traditional therapies that often impact healthy tissues and cause...

Published: 1/2/2026 | Updated: 9/22/2025 | Inventor(s): Kaitlyn Sadtler, Devon Hartigan, Katharina Maisel

Keywords(s):

Category(s): Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology, TherapeuticArea > Immunology

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