Search Results - anti-inflammatory

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Thalidomide Analogs that Inhibit Inflammation and Angiogenesis

Abstract: Thalidomide and its close analogs (lenalidomide and pomalidomide) are widely used to treat a variety of diseases, such as multiple myeloma and other cancers as well as the symptoms of several inflammatory disorders. However, thalidomide is known for its teratogenic adverse effects when first clinically introduced in the 1950s, and is associated...

Published: 4/8/2024 | Inventor(s): Nigel Greig, Weiming Luo, David Tweedie, Nell Vargesson, Shaunna Beedle, William Figg

Keywords(s): anti-angiogenesis, ANTI-INFLAMMATORY, Lenalidomide, Pomalidomide, THALIDOMIDE

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics

NAG-1: A Non-Steroidal Anti-Inflammatory Drug Related Gene Which Has Anti-Tumorigenic Properties

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of inflammatory disease, and their anti-inflammatory effects are believed to result from their ability to inhibit the formation of prostaglandins by prostaglandin H synthase (COX). Two forms of prostaglandin H have been identified, COX-1 and COX-2. The former seems to...

Published: 7/25/2024 | Inventor(s): Richard Diaugustine, Baek Seung, Thomas Eling

Keywords(s): ANTI-INFLAMMATORY, Anti-Tumorigenic, CAXXXX, CBXXXX, CXXXXX, Diagnostics, DRUG, Duke DNA Project, GAXXXX, GBXXXX, Gene, GXXXXX, NAG-1, Non-Steroidal, Patent Category - Biotechnology, PROPERTIES, Protein, RELATED, screening, SECRETED, That, therapeutics

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Oncology