Search Results - carissa+grose

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Improved Production of Prenylated Protein in Insect Cells

Abstract: KRAS and other Ras-family enzymes are an important component of over 30% of human cancers, however, no effective therapeutics targeting Ras or Ras-driven cancers are currently available. The production of Ras proteins in vitro is required for the identification and characterization of Ras targeting drugs. An important step in producing the...

Published: 5/22/2024 | Inventor(s): Dominic Esposito, Carissa Grose, William Gillette

Keywords(s): CANCER, KRAS, RAS, RESEARCH MATERIAL

Category(s): Application > Research Materials, TherapeuticArea > Oncology, Collaboration Sought > Licensing

Bac-2-the-Future: An Improved System for Production of Recombinant Baculovirus

Abstract: Baculoviruses have been used for decades to produce proteins in insect cell hosts. Current systems for generating recombinant baculovirus have several shortcomings which prevent their easy use in high-throughput applications. Researchers within the Frederick National Laboratory for Cancer Research have developed an improved system called...

Published: 5/22/2024 | Inventor(s): Dominic Esposito, Carissa Grose

Keywords(s): B2F, Bac-2-the-Future, Baculovirus, Esposito, Insect Cells, Protein Production

Category(s): TherapeuticArea > Gastroenterology, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, TherapeuticArea > Reproductive Health, TherapeuticArea > Immunology, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Nephrology