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Mice with a Conditional LoxP-Flanked Glucosylceramide Synthase Allele Controlling Glycosphingolipid Synthesis

Glycosphingolipids are organizational building blocks of plasma membranes that participate in key cellular functions, such as signaling and cell-to-cell interactions. Glucosylceramide synthase - encoded by the Ugcg gene - controls the first committed step in the major pathway of glycosphingolipid synthesis. Global disruption of the Ugcg gene in mice...

Published: 7/25/2024 | Inventor(s): Richard Proia

Keywords(s): ACXXXX, AXXXXX, Carrying, ESTABLISHMENT, Floxed, Gene, glucosylceramide, Mice, RXXXXX, SYNTHASE, Ugcg

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials