Search Results - david+scott

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Molecular Classification of Primary Mediastinal Large B Cell Lymphoma Using Formalin-Fixed, Paraffin-Embedded Tissue Specimens

Abstract: Primary mediastinal B-cell lymphoma (PMBCL) is an aggressive type of non-Hodgkin lymphoma that mostly occurs in people between the ages of 30-40. It accounts for 5-7% of all aggressive lymphomas. The diagnosis of PMBCL is challenging as the histological features of PMBCL overlap with diffuse large B-cell lymphoma (DLBCL), another most common...

Published: 4/8/2024 | Inventor(s): Louis Staudt, Lisa Rimsza, David Scott, George Wright, Anja Mottok, Christian Steid, Elaine Jaffe, Randy Gascoyne, Elias Guerri, Elias Guerri, Elias Guerri, Andreas Rosenwald, Kai Fu, Timothy Greiner, Erlend Smeland, Jan Delabie, Rita Braziel, Wing Chan, Joo Song, Dennis Weisenburger, German Ott, James Cook

Keywords(s): assay, Diffuse Large B Cell Lymphoma, DLBCL, FFPE, Formalin-fixed, GENE EXPRESSION, paraffin-embedded biopsies, PMBCL, Primary Mediastinal Large B Cell Lymphoma, Staudt

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics

Clinical Outcome Predictors for Mantle Cell Lymphoma

Abstract: Mantle cell lymphoma (MCL) is a group of aggressive B-cell lymphomas displaying heterogeneous outcomes after treatment. Some patients have the slowly progressing disease that does not require immediate treatment, while others have a disease that rapidly progresses despite highly aggressive treatment. A number of prognostic tools have been...

Published: 8/14/2024 | Inventor(s): Louis Staudt, David Scott, George Wright, Andreas Rosenwald, Pau Abrisqueta, Rita Braziel, Elias Guerri, Wing Chan, Joseph Connors, Diego Villa, Kai Fu, Randy Gascoyne, Timothy Greiner, Elaine Jaffe, Graham Slack, James Cook, Jan Delabie, German Ott, Lisa Rimsza, Dennis Weisenburger, Anja Mottok, Pedro Jares

Keywords(s): B-cell lymphomas, Gene expression profile, Mantle cell lymphoma, Prognostic tool

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology

Process for Practical, Scalable, Commercially-viable Method for the Synthesis of Enantio-enriched Aminoalcohols, Including the Novel Antifungal VT-1129 Used to Treat Cryptococcal Meningitis

This technology relates to the discovery and development of a practical, scalable, and commercially viable method for the synthesis of the novel antifungal VT-1129. Cryptococcal meningitis (CM) is a fungal infection that is particularly prevalent in immune-compromised patients and can be treated by VT-1129. CM has a current estimated patient population...

Published: 10/28/2024 | Inventor(s): Mark Behnke, Scott David, Douglas Fry, William Hoekstra, Christopher Yates, Asaf Alimardanov

Keywords(s): Acid, Alcohol, Aminoalcohols, Benzenesulfonic, BSA., Co-crystal, Containing, Derivatives, Enantioenriched, Fragment, Including, Listed LPM Nguyen-Antczak as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PROCESS, Synthesis, Tertiary, THOSE, VEXXXX, VT-1129, WMXXXX

Category(s): Application > Consumer Products, TherapeuticArea > Neurology