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Synthetic Lethality-mediated Precision Oncology via the Tumor Transcriptome

Abstract: The use of tumor transcriptomics for precision oncology has made significant advances, mainly by identifying cancer driver genes or actionable mutations for treatment with targeted therapies. However, this strategy misses out on broader genetic interactions that could reveal additional biologically testable biomarkers for therapy response...

Published: 4/8/2024 | Inventor(s): Eytan Ruppin, Joo Lee

Keywords(s): Genetic Interactions, Patient Stratification, Precision Diagnostics, Precision Oncology, Ruppin, Synthetic Lethality, Transcriptome

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology