Search Results - patient+stratification

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A Gene-Based Prognostic for Hepatocellular Carcinoma Patient Response to Adjuvant Transcatheter Arterial Chemoembolization

Abstract: Hepatocellular Carcinoma (HCC) is one of the most common cancers worldwide with largely unfavorable outcomes due to a lack of effective treatment options for patients in the later state of disease. The gold standard of care for HCC patients with intermediate to locally advanced tumors is transcatheter arterial chemoembolization (TACE), a procedure...

Published: 4/8/2024 | Inventor(s): Xin Wei Wang, Valerie Miller

Keywords(s): Gene-Expression Signature, hepatocellular carcinoma, Patient Stratification, prognostic

Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Synthetic Lethality-mediated Precision Oncology via the Tumor Transcriptome

Abstract: The use of tumor transcriptomics for precision oncology has made significant advances, mainly by identifying cancer driver genes or actionable mutations for treatment with targeted therapies. However, this strategy misses out on broader genetic interactions that could reveal additional biologically testable biomarkers for therapy response...

Published: 4/8/2024 | Inventor(s): Eytan Ruppin, Joo Lee

Keywords(s): Genetic Interactions, Patient Stratification, Precision Diagnostics, Precision Oncology, Ruppin, Synthetic Lethality, Transcriptome

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology