Search Results - gildersleeve

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A Human Monoclonal Antibody Against Deacetylated PNAG for Use as an Antimicrobial Agent

Abstract: Biofilms are complex microbial communities, surface attached and held together by self-produced polymer matrices. These matrices are mainly composed of polysaccharides, secreted proteins and nucleic acids. Poly-N-acetyl glucosamine (PNAG) is a highly conserved surface polysaccharide expressed by a range of bacterial, fungal and protozoan...

Published: 5/22/2024 | Inventor(s): Jeffrey Gildersleeve, Joel Temme

Keywords(s): ANTIMICROBIAL, Biofilm, Deacetyleated Poly-N-Acetyl Glucosamine, dPNAG, Gildersleeve, Mab, Monoclonal Antibody, TG10

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing

A Novel Carbohydrate Antibody to GalNac1-3Gal and Its Application for Cancer Diagnostic and Prognosis

Abstract: Cervical cancer is one of the most common cancers among women worldwide. Currently, physical descriptors such as tumor size and depth are the primary factors used for deciding the course of treatment. Despite significant efforts to identify prognostic biochemical markers or therapeutic targets to improve diagnosis and treatment, none have...

Published: 4/8/2024 | Inventor(s): Jeffrey Gildersleeve, Zhitao Li, Qian Li, Miriam Anver, Donna Butcher

Keywords(s): ANTIBODY, CERVICAL, GaLNAc1-3Gal, Gildersleeve, Immunohistochemical staining, Larynx, Prognostic marker, SKIN, Squamous Cell

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology