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A Human Monoclonal Antibody Against Deacetylated PNAG for Use as an Antimicrobial Agent

Abstract: Biofilms are complex microbial communities, surface attached and held together by self-produced polymer matrices. These matrices are mainly composed of polysaccharides, secreted proteins and nucleic acids. Poly-N-acetyl glucosamine (PNAG) is a highly conserved surface polysaccharide expressed by a range of bacterial, fungal and protozoan...

Published: 5/22/2024 | Inventor(s): Jeffrey Gildersleeve, Joel Temme

Keywords(s): ANTIMICROBIAL, Biofilm, Deacetyleated Poly-N-Acetyl Glucosamine, dPNAG, Gildersleeve, Mab, Monoclonal Antibody, TG10

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing