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Cell Line for Production of Recombinant Human Tissue Inhibitor of Metalloproteinase-2

Abstract: Studies have shown that Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) suppresses tumor growth and tumor-associated angiogenesis. Currently, the main obstacle in using TIMP-2 as a biologic therapeutic has been the inability to produce sufficient quantities of the protein for testing and development. NCI Radiation Oncology Branch (ROB)...

Published: 5/23/2024 | Inventor(s): William Stetler-Stevens, Beiyang Wei

Keywords(s): CANCER, Cerebrovascular Infarct, HEK-293F Cell Line, Ischemic and Neurodegenerative Diseases, Myocardial Infarct, Stetler-Stevenson, TIMP-2, Tissue Inhibitor of Metalloproteinases 2, tumor suppressor

Category(s): TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Research Materials, Collaboration Sought > Licensing