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The Use of alpha-4 beta-7 integrin Inhibitors to Inhibit HIV Transmission and Infection

This invention involves the use of inhibitors of alpha-4 beta-7 (a4b7) integrin to inhibit HIV transmission/infection, as a prophylactic to inhibit onset of the acute stage of HIV infection or to treat HIV infection. The a4b7 integrin inhibitors were previously developed for use in other diseases, such as multiple sclerosis or inflammatory bowel disease. a4b7...

Published: 7/25/2024 | Inventor(s): Anthony Fauci, Claudia Cicala, Diana Goode, James Arthos

Keywords(s): ANTAGONISTS, BBXXXX, BETWEEN, DB4AXX, DB4XXX, DBXXXX, Direct, DXXXXX, gp120, HIV, INTERACTION, Intregrin, VLXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease