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Novel Acylthiol Compositions and Methods of Making and Using Them Against HIV

This invention provides a novel family of acylthiols and uses thereof. More specifically, this invention provides effective inhibitors of HIV that selectively target its highly conserved nucleocapsid protein (NCp7) by interacting with metal chelating structures of a zinc finger-containing protein. Because of the mutationally intolerant nature of NCp7,...

Published: 7/25/2024 | Inventor(s): John Inman, Atul Goel, Ettore Appella, James Turpin, Marco Schito

Keywords(s): DB4XXX, DBXXXX, DXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics