Search Results - marco+schito

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Bile Acids and Other Agents that Modulate the Gut Microbiome for the Treatment of Liver Cancer

Abstract: Primary liver tumors and secondary hepatic malignancies are among the leading causes of cancer-related deaths. Liver metastases account for 95% of all hepatic cancers, and the liver is the most common site for organ metastasis in the body. The gut microbiome serves an important role in antitumor immunity regulating the efficacy of chemo- and...

Published: 4/8/2024 | Inventor(s): Tim Greten, Chi Ma

Keywords(s): Bile Acid, Greten, Liver cancer, Natural Killer T Cells, NKT cells

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing

Novel Acylthiol Compositions and Methods of Making and Using Them Against HIV

This invention provides a novel family of acylthiols and uses thereof. More specifically, this invention provides effective inhibitors of HIV that selectively target its highly conserved nucleocapsid protein (NCp7) by interacting with metal chelating structures of a zinc finger-containing protein. Because of the mutationally intolerant nature of NCp7,...

Published: 7/25/2024 | Inventor(s): John Inman, Atul Goel, Ettore Appella, James Turpin, Marco Schito

Keywords(s): DB4XXX, DBXXXX, DXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics