Search Results - katherine+roche

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Development of a Polyclonal Antibody for Neuroligin 4 pThr707 and a Polyclonal Antibody for Neuroligin 1 pTHR739

This invention includes the generation and use of two polyclonal antibodies that specifically recognizes the phosphorylation site pThr707 of Neuroligin 4 and pThr739 of Neuroligin 1. A peptide of the site around the phosphorylation site was generated and injected into rabbits to create an immune response. Serum was collected from the rabbits that was...

Published: 7/25/2024 | Inventor(s): Michael Bemben, John Badger, Katherine Roche

Keywords(s): 1, 4, ANTIBODY, Development, Listed LPM Contreras as of 4/15/2015, Neuroligin, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PThr707, THR739, VEXXXX, WBXXXX, WIXXXX, XAXXXX

Category(s): TherapeuticArea > Neurology, TherapeuticArea > Immunology, Application > Diagnostics, ResearchProducts > Antibodies, Application > Research Materials

mGluR5 Tumor Mouse Model

Glutamate receptor mGluR5 has been reported to function in the brain. There were no prior reports of it being involved in melanoma. The NIH investigators have discovered that when over expressed in transgenic animals, mGluR5 induces melanoma. The establishment of an mGluR5 tumor mouse model will provide a unique opportunity to help elucidate the mechanisms...

Published: 7/25/2024 | Inventor(s): Kyu Yeong Choi, Katherine Roche

Keywords(s): CCXXXX, CXXXXX, MGluR5, Model, Mouse, RXXXXX, tumor

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology