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Gs Alpha LoxP (Gnastm1Lsw) Mouse Model for Metabolism Studies

Generation of a floxed Gnsa gene for the G-protein Gs alpha (Gsalpha) for the construction of conditional knockout mice. The heterotrimeric G protein Gsalpha couples many receptors to adenylyl cyclase and is essential for hormone-stimulated cAMP generation. Previous mouse models with germ-line mutations in Gnas, the gene that encodes Gsalpha had limited...

Published: 7/25/2024 | Inventor(s): Lee Weinstein

Keywords(s): ALPHA, AXXXXX, GCXXXX, Ghas, GS, GXXXXX, LOXP, Mouse, RXXXXX, Tm1LSW

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Therapeutics